Details
Disease Name Frontotemporal Dementia
Nocoding RNA Name hsa-miR-659
Expression Pattern mutated
Species Homo sapiens
Detection Methods genotyping, ELISA, Real-time PCR, Luciferase Reporter Assay etc.
Target GRN
Tissue brain
Treatment N/A
PubMed ID 18723524
Year 2008
Detail Description We further demonstrate that miR-659 can regulate GRN expression in vitro, with miR-659 binding more efficiently to the high risk T-allele of rs5848 resulting in augmented translational inhibition of GRN.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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