Details
Disease Name Glioblastoma
Nocoding RNA Name hsa-miR-873
Expression Pattern down-regulated
Species Homo sapiens
Detection Methods Flow Cytometry,Western Blot,Colony Formation Assays etc.
Target IGF2BP1
Tissue brain(brain tumor tissue)
Treatment N/A
PubMed ID 25670861
Year 2015
Detail Description microRNA-873 (miR-873) was expressed at low levels in GBM and that the overexpression of miR-873 dramatically reduced the cell proliferation, migration, and invasion of GBM cells.miR-873 negatively affected the carcinogenesis and metastasis of GBM by down-regulating the expression of IGF2BP1, which stabilizes the mRNA transcripts of its target genes.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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