Details
Disease Name Glioblastoma
Nocoding RNA Name hsa-miR-92a
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods Quantitative Real-time PCR,Western Blot,miRNA locked nucleic acid in situ hybridization,immunohistochemistry,Luciferase Reporter Assay etc.
Target BCL2L11
Tissue brain(brain tumor tissue)
Treatment N/A
PubMed ID 22895567
Year 2012
Detail Description high expression of miR-92a in human glioma specimens is significantly correlated with low levels of BCL2L11 (Bim) protein and high-grade glioma.Bim is a direct functional target of miR-92a. Introducing Bim cDNA without 3'UTR abrogates miR-92a-induced cell survival.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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