Three hundred and fourteen (314) miRNAs were detected upon profiling of total RNA isolated from cohort 1 patients’ peripheral blood samples. Further statistical analyses based on Benjamini-Hochberg FDR correction (p value < 0.05) and fold-change cut-offs (>1.2 or <-1.2), resulted in 105 statistically significant miRNAs. Quantitative PCR was performed on 10 miRNAs (p< 0.0001) to validate our microarray data. Among the 105 miRNAs, 58 were downregulated (fold change <-1.2) while 47 were upregulated.
NSDNA: The Nervous System Disease NcRNAome Atlas
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