Details
Disease Name Neuroblastoma
Nocoding RNA Name lncUSMycN
Expression Pattern up-regulated
Species Homo sapiens
Detection Methods RT-PCR,siRNA,Chromatin immunoprecipitation assays etc.
Target N/A
Tissue brain(brain tumor tissue)
Treatment N/A
PubMed ID 24906397
Year 2014
Detail Description The lncUSMycN gene was coamplified with MYCN in 88 of 341 human neuroblastoma tissues. lncUSMycN RNA bound to the RNA-binding protein NonO, leading to N-Myc RNA upregulation and neuroblastoma cell proliferation. High levels of lncUSMycN and NonO expression in human neuroblastoma tissues independently predicted poor patient prognoses.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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