| Disease Name |
Alzheimer Disease |
| Nocoding RNA Name |
mmu-miR-181c |
| Expression Pattern |
down-regulated |
| Species |
Mus musculus |
| Detection Methods |
microarray,Quantitative Real-time PCR,Luciferase Reporter Assay,Western Blot,Immunofluorescence etc. |
| Target |
crmp2 |
| Tissue |
hippocampus |
| Treatment |
N/A
|
| PubMed ID |
27423553 |
| Year |
2016 |
| Detail Description |
Our results indicated that miR-181 levels were increased with aging in the hippocampus and down-regulated in the AD mouse model. The down-regulation of miR-181c leads to the de-repression of its target gene, crmp2, at the posttranscriptional level, which might play a role in the pathogenesis of Alzheimer's disease. |
|