Details
Disease Name Alzheimer Disease
Nocoding RNA Name mmu-miR-181c
Expression Pattern down-regulated
Species Mus musculus
Detection Methods microarray,Quantitative Real-time PCR,Luciferase Reporter Assay,Western Blot,Immunofluorescence etc.
Target crmp2
Tissue hippocampus
Treatment N/A
PubMed ID 27423553
Year 2016
Detail Description Our results indicated that miR-181 levels were increased with aging in the hippocampus and down-regulated in the AD mouse model. The down-regulation of miR-181c leads to the de-repression of its target gene, crmp2, at the posttranscriptional level, which might play a role in the pathogenesis of Alzheimer's disease.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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