| Details |
| Disease Name | Neuroblastoma |
| Nocoding RNA Name | ncRAN |
| Expression Pattern | up-regulated |
| Species | Homo sapiens |
| Detection Methods | RT-PCR,Northern Blot,siRNA etc. |
| Target | N/A |
| Tissue | brain(brain tumor tissue) |
| Treatment | N/A |
| PubMed ID | 19287950 |
| Year | 2009 |
| Detail Description | In analysis of 70 patients with sporadic neuroblastoma, the high levels of ncRAN mRNA expression were significantly associated with poor outcome of the patients (p<0.001). The multivariate analysis showed that expression of ncRAN mRNA was an independent prognostic factor among age, stage, origin and MYCN expression. Ectopic expression of ncRAN induced transformation of NIH3T3 cells in soft agar, while knockdown of endogenous ncRAN with RNA interference significantly inhibited cell growth in SH-SY5Y cells. |
NSDNA: The Nervous System Disease NcRNAome Atlas
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