Details
Disease Name Epilepsy, Temporal Lobe
Nocoding RNA Name rno-miR-540-5p
Expression Pattern up-regulated
Species Rattus norvegicus
Detection Methods high-throughput sequencing etc.
Target N/A
Tissue brain(hippocampus)
Treatment N/A
PubMed ID 24751812
Year 2014
Detail Description After comparing the miRNA expression profile in control group and chronic TLE group, we detected 25 miRNAs that were differentially expressed in rat hippocampus. Among these miRNAs, fourteen miRNAs were found to be up-regulated whilst eleven miRNAs were down-regulated.Afterwards, six miRNAs (miR-455-3p, miR-345-3p, miR-423-3p, novel miR-54,miR-365-5p, and miR-296-5p) were screened out based on the criteria mentioned in ‘‘Methods’’ section, and qRT-PCR was performed to validate the alterations of these miRNA.

 

NSDNA: The Nervous System Disease NcRNAome Atlas

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