Overview

ODrugCP provides users friendly interface for exploring otoptimized drug combination regimens related to pan-cancer. The current version of ODrugCP documents 687 optimized drug combination regimens , 274 risk pathways and 15426 crosstalk between risk pathways for 21 cancers.


Home

1, The body maps can facilitate quick browse of 21 cancers for the listed tissues.
2, The introduction of ODrugCP.
3, A quick search for filtering entries. Users can input cancers, mRNAs, miRNAs, pathways and drugs of interest.
4, Drug combinations that appear in only one cancer.
5, Optimal drug combination plans present in more than three cancers.
6, Top 5 drug combinations in 21 cancers.


Browse

Hierarchical classifications of cancers, drugs, targets and pathways are presented in the browse page. The matching records will show by clicking name of interest.
1, All 21 cancer-related drugs, targets, and pathways names are presented. By clicking on the name, records that contain this will be returned.
2, Basic information about the number of individual items in 21 cancers:
Cancer(Cancer Abbreviations)
DE mRNA(Number of differentially expressed mRNAs per cancer)
DE miRNA(Number of differentially expressed miRNAs per cancer)
Risk mRNA(Number of risk mRNAs per cancer)
Risk miRNA(Number of risk miRNAs per cancer)
Risk pathway(Number of risk pathways per cancer)
Pathway crosstalk(Number of pathway crosstalk across risk pathways per cancer)
Drug combination(Number of drug combinations per cancer)
3, Basic information about optimization in cancer drug combination:
Cancer(Cancer Abbreviations)
Drug1, Drug2(Two drugs used in combination cancer)
TargetINPathway(Through which targets the drug perturbs the pathway)
Risk pathway(Perturbed pathways in drug combination)