• LnCeCell 2.0 New
    - "One Cell, One Network, One World".
    LnCeCell 2.0 is an updated resource for lncRNA-associated
    ceRNA networks and web tools based on single-cell and
    spatial transcriptomics sequencing data.
  • New features of LnCeCell 2.0
    - Collection of scRNA-seq (>1,000,000 cells) and stRNA-seq (>360,000 spatial spots) data.
    - Over 15,000 experimentally supported lncRNA biomarkers.
    - Cell type/state/function and subcellular locations through manual curation.
    - Dynamic change of the ceRNA network along the cell trajectory.
    - A panel of 8 comprehensive analysis tools and 16 mini analysis tools . . .

TOOLS PANELComprehensive Analysis Tools

Investigate gene expression, ceRNA abundance and their association with different cell populations, cell types, states, primary/metastatic sites, etc.

Illustrate the detailed ceRNA distribution of cell populations and explore the dynamic change of the ceRNA network along the cell developmental trajectory.

Explore causative interplay between ceRNA regulation and cell states along the cell developmental trajectory.

Explore causative interplay between ceRNA regulation and functions (GO terms, pathways, hallmarks, etc.) along the cell developmental trajectory.

Perform multi-level crosstalk analysis between ceRNA networks and functional states that contribute to individual disease pathology and cell fate in an interactive 3D view.

Perform multi-level crosstalk analysis between ceRNA networks and functional states at spatial spot resolution in an interactive 3D view.

An overview of ceRNA distribution across pan-cancer, normal tissues/organs at single-cell resolution.

An overview of ceRNA distribution across pan-cancer, normal tissues/organs at spatial point resolution.

Mini Analysis Tools

CellCluster
CellCluster
CellTraject
CellTrajectory
CeCellExp
Expression
CeHallmark
Hallmark
CeFunction
Function
CeNet
Network
CeLocation
Celllocation
LncMarker
Celllocation
Survival
Spatial
CellState
StatePseu
CellFunction
FuncPseu
CeStateTalk
CellStateInterplay
CeFuncTalk
FuncStateInterplay
SpatialView
Spatial
SpatialCe
Spatial
SpatialFunction
Spatial

LnCeCell 2.0 New Features

257 Datasets

1.37M+ Cells

86 Diseases

836,581 CeRNAs

127 Publications

Database Dataset (scRNA-seq) Dataset (stRNA-seq) Disease Normal organs/tissues CeRNAs Biomarkers Tools
LnCeCell 1.0 40 0 25 0 93,307 9,406 7
LnCeCell 2.0 204 53 86 80 836,581 14,768 24
Fold increase

Citation

LnCeCell 2.0: an updated resource for lncRNA-associated ceRNA networks and web tools based on single-cell and spatial transcriptomics sequencing data.

LnCeCell: a comprehensive database of predicted lncRNA-associated ceRNA networks at single-cell resolution.

DatabaseOur works

CellTracer
222 Datasets
1.94M+ Cells
42 Disease

A comprehensive database to dissect the causative multilevel interplay contributing to cell development trajectories.
Article Website

LncACTdb 3.0
62 Datasets
5669 CeRNAs
1W Biomarkers

An updated database of experimentally supported ceRNA interactions and personalized networks contributing to precision medicine.
Article Website

CellMarker 2.0
108 Datasets
2.6W+ Cell markers
656 tissues

An updated database of manually curated cell markers in human/mouse and web tools based on scRNA-seq data.
Article Website

Lnc2Cancer 3.0
9254 LncRNA-cancer events
1049 CircRNA-cancer events

An updated resource for experimentally supported lncRNA/circRNA cancer associations and web tools based on RNA-seq and scRNA-seq data.
Article Website

LincSNP 3.0
1.48M+ SNP
4.31M+ LD SNP

An updated database for linking functional variants to human long non-coding RNAs, circular RNAs and their regulatory elements.
Article Website

LnCeVar
1.14W+ somatic mutation–ceRNA events
11.2W+ CNV–ceRNA events

A comprehensive database of genomic variations that disturb ceRNA network regulation.
Article Website