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RBP List
The enrichment of RBPs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | RBP ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| BRCA | ENSG00000111144 | LTA4H | Antimicrobials | 1.145e-03 | 6.381e-03 | -0.3239 | -0.9977 | protective | details |
| BRCA | ENSG00000111144 | LTA4H | Cytokines | 1.148e-03 | 6.381e-03 | -0.3614 | -0.9977 | protective | details |
| BRCA | ENSG00000111144 | LTA4H | Cytokine Receptors | 1.171e-03 | 6.381e-03 | -0.3644 | -0.9977 | protective | details |
| BRCA | ENSG00000111144 | LTA4H | TGFb Family Member | 1.502e-03 | 6.381e-03 | -0.5551 | -0.997 | protective | details |
| BRCA | ENSG00000108984 | MAP2K6 | Interleukins Recepto... | 1.852e-03 | 1.049e-02 | 0.5842 | 0.9963 | protective | details |
| BRCA | ENSG00000108984 | MAP2K6 | Natural Killer Cell ... | 1.767e-03 | 1.049e-02 | 0.3775 | 0.9965 | protective | details |
| BRCA | ENSG00000108984 | MAP2K6 | TCR signaling Pathwa... | 1.789e-03 | 1.049e-02 | 0.3954 | 0.9964 | protective | details |
| BRCA | ENSG00000168906 | MAT2A | TNF Family Members R... | 2.123e-03 | 1.672e-02 | -0.5348 | -0.9958 | risk | details |
| BRCA | ENSG00000232119 | MCTS1 | Cytokine Receptors | 1.208e-03 | 1.417e-02 | -0.3064 | -0.9976 | risk | details |
| BRCA | ENSG00000232119 | MCTS1 | TGFb Family Member R... | 1.667e-03 | 1.417e-02 | -0.6125 | -0.9967 | risk | details |
| BRCA | ENSG00000124383 | MPHOSPH10 | TCR signaling Pathwa... | 2.410e-03 | 1.269e-02 | 0.3227 | 0.9952 | risk | details |
| BRCA | ENSG00000172172 | MRPL13 | Cytokine Receptors | 2.404e-03 | 2.146e-02 | -0.2548 | -0.9952 | risk | details |
| BRCA | ENSG00000163319 | MRPS18C | Cytokine Receptors | 1.208e-03 | 2.053e-02 | -0.2925 | -0.9976 | risk | details |
| BRCA | ENSG00000122140 | MRPS2 | Antigen Processing a... | 2.320e-03 | 1.578e-02 | 0.3924 | 0.9954 | risk | details |
| BRCA | ENSG00000122140 | MRPS2 | Chemokines | 2.137e-03 | 1.578e-02 | 0.3164 | 0.9957 | risk | details |
| BRCA | ENSG00000147649 | MTDH | Cytokines | 1.490e-03 | 2.534e-02 | -0.2529 | -0.997 | risk | details |
| BRCA | ENSG00000164134 | NAA15 | Cytokines | 1.618e-03 | 2.751e-02 | -0.2104 | -0.9968 | risk | details |
| BRCA | ENSG00000188613 | NANOS1 | Interleukins Recepto... | 2.364e-03 | 2.388e-02 | 0.4583 | 0.9953 | risk | details |
| BRCA | ENSG00000101882 | NKAP | Cytokine Receptors | 1.572e-03 | 2.673e-02 | -0.3437 | -0.9969 | risk | details |
| BRCA | ENSG00000115761 | NOL10 | Interleukins Recepto... | 2.457e-03 | 1.115e-02 | 0.4084 | 0.9951 | risk | details |