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RBP List
The enrichment of RBPs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | RBP ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| BRCA | ENSG00000198585 | NUDT16 | Antigen Processing a... | 2.331e-03 | 1.095e-02 | -0.3328 | -0.9953 | protective | details |
| BRCA | ENSG00000198585 | NUDT16 | Interleukins Recepto... | 2.237e-03 | 1.095e-02 | -0.3978 | -0.9955 | protective | details |
| BRCA | ENSG00000198585 | NUDT16 | Natural Killer Cell ... | 2.299e-03 | 1.095e-02 | -0.3556 | -0.9954 | protective | details |
| BRCA | ENSG00000227345 | PARG | Cytokines | 1.901e-03 | 3.232e-02 | -0.2493 | -0.9962 | risk | details |
| BRCA | ENSG00000059378 | PARP12 | TGFb Family Member | 1.597e-03 | 1.064e-02 | -0.5571 | -0.9968 | protective | details |
| BRCA | ENSG00000169174 | PCSK9 | Antimicrobials | 1.305e-03 | 6.967e-03 | 0.3213 | 0.9974 | protective | details |
| BRCA | ENSG00000169174 | PCSK9 | Chemokines | 1.546e-03 | 6.967e-03 | 0.4935 | 0.9969 | protective | details |
| BRCA | ENSG00000169174 | PCSK9 | Cytokines | 1.307e-03 | 6.967e-03 | 0.4582 | 0.9974 | protective | details |
| BRCA | ENSG00000169174 | PCSK9 | TGFb Family Member | 1.639e-03 | 6.967e-03 | 0.6409 | 0.9967 | protective | details |
| BRCA | ENSG00000164902 | PHAX | Antimicrobials | 1.862e-03 | 8.517e-03 | -0.2887 | -0.9963 | risk | details |
| BRCA | ENSG00000164902 | PHAX | Chemokines | 2.004e-03 | 8.517e-03 | -0.3171 | -0.996 | risk | details |
| BRCA | ENSG00000164902 | PHAX | Cytokines | 1.880e-03 | 8.517e-03 | -0.2073 | -0.9962 | risk | details |
| BRCA | ENSG00000164902 | PHAX | TNF Family Members R... | 1.923e-03 | 8.517e-03 | -0.5918 | -0.9962 | risk | details |
| BRCA | ENSG00000215021 | PHB2 | Antigen Processing a... | 2.463e-03 | 9.471e-03 | 0.4106 | 0.9951 | protective | details |
| BRCA | ENSG00000215021 | PHB2 | Chemokines | 2.415e-03 | 9.471e-03 | 0.3278 | 0.9952 | protective | details |
| BRCA | ENSG00000215021 | PHB2 | TNF Family Members R... | 2.304e-03 | 9.471e-03 | 0.5419 | 0.9954 | protective | details |
| BRCA | ENSG00000100941 | PNN | TCR signaling Pathwa... | 1.473e-03 | 2.504e-02 | 0.4407 | 0.9971 | protective | details |
| BRCA | ENSG00000137054 | POLR1E | Antigen Processing a... | 2.146e-03 | 8.458e-03 | 0.3707 | 0.9957 | protective | details |
| BRCA | ENSG00000137054 | POLR1E | Antimicrobials | 2.488e-03 | 8.458e-03 | 0.2709 | 0.995 | protective | details |
| BRCA | ENSG00000137054 | POLR1E | Chemokines | 2.188e-03 | 8.458e-03 | 0.3163 | 0.9956 | protective | details |