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RBP List
The enrichment of RBPs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | RBP ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| BRCA | ENSG00000164506 | STXBP5 | Antimicrobials | 2.217e-03 | 1.256e-02 | -0.2499 | -0.9956 | risk | details |
| BRCA | ENSG00000164506 | STXBP5 | Chemokines | 2.160e-03 | 1.256e-02 | -0.3621 | -0.9957 | risk | details |
| BRCA | ENSG00000078269 | SYNJ2 | Antigen Processing a... | 2.217e-03 | 7.834e-03 | -0.3621 | -0.9956 | risk | details |
| BRCA | ENSG00000078269 | SYNJ2 | Antimicrobials | 2.304e-03 | 7.834e-03 | -0.2674 | -0.9954 | risk | details |
| BRCA | ENSG00000078269 | SYNJ2 | Chemokines | 2.242e-03 | 7.834e-03 | -0.3397 | -0.9955 | risk | details |
| BRCA | ENSG00000078269 | SYNJ2 | Cytokines | 2.257e-03 | 7.834e-03 | -0.2149 | -0.9955 | risk | details |
| BRCA | ENSG00000078269 | SYNJ2 | TGFb Family Member R... | 1.976e-03 | 7.834e-03 | 0.6785 | 0.996 | risk | details |
| BRCA | ENSG00000172403 | SYNPO2 | TGFb Family Member R... | 1.845e-03 | 1.246e-02 | 0.6402 | 0.9963 | protective | details |
| BRCA | ENSG00000172403 | SYNPO2 | TNF Family Members R... | 2.304e-03 | 1.246e-02 | -0.53 | -0.9954 | protective | details |
| BRCA | ENSG00000133112 | TPT1 | Chemokine Receptors | 1.802e-03 | 1.327e-02 | -0.4588 | -0.9964 | protective | details |
| BRCA | ENSG00000133112 | TPT1 | Cytokines | 2.342e-03 | 1.327e-02 | 0.2596 | 0.9953 | protective | details |
| BRCA | ENSG00000133112 | TPT1 | TCR signaling Pathwa... | 1.783e-03 | 1.327e-02 | -0.3516 | -0.9964 | protective | details |
| BRCA | ENSG00000121060 | TRIM25 | Cytokines | 1.712e-03 | 1.251e-02 | -0.2848 | -0.9966 | risk | details |
| BRCA | ENSG00000121060 | TRIM25 | Natural Killer Cell ... | 2.141e-03 | 1.251e-02 | 0.406 | 0.9957 | risk | details |
| BRCA | ENSG00000121060 | TRIM25 | TCR signaling Pathwa... | 2.208e-03 | 1.251e-02 | 0.4167 | 0.9956 | risk | details |
| BRCA | ENSG00000072756 | TRNT1 | Cytokines | 1.550e-03 | 1.094e-02 | -0.3274 | -0.9969 | risk | details |
| BRCA | ENSG00000072756 | TRNT1 | TGFb Family Member | 1.859e-03 | 1.094e-02 | -0.4557 | -0.9963 | risk | details |
| BRCA | ENSG00000072756 | TRNT1 | TNF Family Members R... | 1.931e-03 | 1.094e-02 | -0.5996 | -0.9961 | risk | details |
| BRCA | ENSG00000075886 | TUBA3D | Antigen Processing a... | 2.433e-03 | 1.427e-02 | -0.349 | -0.9951 | protective | details |
| BRCA | ENSG00000075886 | TUBA3D | Natural Killer Cell ... | 2.421e-03 | 1.427e-02 | -0.3592 | -0.9952 | protective | details |