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TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| ACC | ENSG00000181090 | EHMT1 | Natural Killer Cell ... | 1.565e-03 | 1.252e-02 | -0.4605 | -0.9969 | risk | details |
| ACC | ENSG00000130511 | SSBP4 | Antigen Processing a... | 1.873e-03 | 1.498e-02 | -0.4588 | -0.9963 | risk | details |
| ACC | ENSG00000130511 | SSBP4 | Antimicrobials | 1.786e-03 | 1.498e-02 | -0.3167 | -0.9964 | risk | details |
| ACC | ENSG00000171988 | JMJD1C | Antigen Processing a... | 1.361e-03 | 2.177e-02 | -0.4788 | -0.9973 | risk | details |
| ACC | ENSG00000169252 | ADRB2 | Antigen Processing a... | 1.458e-03 | 2.097e-02 | 0.5182 | 0.9971 | protective | details |
| ACC | ENSG00000169925 | BRD3 | Antigen Processing a... | 1.453e-03 | 2.326e-02 | -0.4395 | -0.9971 | risk | details |
| ACC | ENSG00000133243 | BTBD2 | Antigen Processing a... | 1.661e-03 | 2.658e-02 | -0.4822 | -0.9967 | risk | details |
| ACC | ENSG00000143418 | CERS2 | Antigen Processing a... | 2.193e-03 | 1.754e-02 | 0.5023 | 0.9956 | protective | details |
| ACC | ENSG00000143418 | CERS2 | Cytokines | 1.754e-03 | 1.754e-02 | -0.3271 | -0.9965 | protective | details |
| ACC | ENSG00000109089 | CDR2L | Cytokines | 2.370e-03 | 2.991e-02 | 0.3179 | 0.9953 | risk | details |
| ACC | ENSG00000100150 | DEPDC5 | Antigen Processing a... | 2.445e-03 | 3.575e-02 | -0.5065 | -0.9951 | risk | details |
| ACC | ENSG00000141994 | DUS3L | TCR signaling Pathwa... | 2.062e-03 | 3.299e-02 | -0.5203 | -0.9959 | risk | details |
| ACC | ENSG00000161202 | DVL3 | Antigen Processing a... | 2.237e-03 | 3.579e-02 | -0.4694 | -0.9955 | risk | details |
| ACC | ENSG00000196208 | GREB1 | Natural Killer Cell ... | 1.656e-03 | 2.649e-02 | -0.4448 | -0.9967 | risk | details |
| ACC | ENSG00000172349 | IL16 | Cytokine Receptors | 2.323e-03 | 1.239e-02 | 0.3869 | 0.9954 | protective | details |
| ACC | ENSG00000172349 | IL16 | Natural Killer Cell ... | 1.297e-03 | 1.085e-02 | 0.5027 | 0.9974 | protective | details |
| ACC | ENSG00000172349 | IL16 | TCR signaling Pathwa... | 1.357e-03 | 1.085e-02 | 0.4893 | 0.9973 | protective | details |
| ACC | ENSG00000003096 | KLHL13 | TCR signaling Pathwa... | 1.880e-03 | 3.008e-02 | 0.4818 | 0.9962 | protective | details |
| ACC | ENSG00000162413 | KLHL21 | TCR signaling Pathwa... | 1.499e-03 | 2.399e-02 | 0.4599 | 0.997 | protective | details |
| ACC | ENSG00000109790 | KLHL5 | Antigen Processing a... | 1.546e-03 | 2.473e-02 | -0.4752 | -0.9969 | risk | details |