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TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| ACC | ENSG00000235750 | KIAA0040 | Cytokine Receptors | 2.245e-03 | 1.197e-02 | 0.4087 | 0.9955 | protective | details |
| ACC | ENSG00000235750 | KIAA0040 | Natural Killer Cell ... | 1.235e-03 | 1.018e-02 | 0.5306 | 0.9975 | protective | details |
| ACC | ENSG00000235750 | KIAA0040 | TCR signaling Pathwa... | 1.272e-03 | 1.018e-02 | 0.5151 | 0.9975 | protective | details |
| ACC | ENSG00000136153 | LMO7 | Antigen Processing a... | 1.435e-03 | 2.296e-02 | -0.5732 | -0.9971 | risk | details |
| ACC | ENSG00000127663 | KDM4B | Natural Killer Cell ... | 1.597e-03 | 1.852e-02 | -0.4304 | -0.9968 | risk | details |
| ACC | ENSG00000127663 | KDM4B | TGFb Family Member | 2.315e-03 | 1.852e-02 | 0.6347 | 0.9954 | risk | details |
| ACC | ENSG00000198502 | HLA-DRB5 | Antigen Processing a... | 1.370e-03 | 4.147e-03 | 0.5459 | 0.9973 | protective | details |
| ACC | ENSG00000198502 | HLA-DRB5 | Antimicrobials | 1.170e-03 | 4.147e-03 | 0.4013 | 0.9977 | protective | details |
| ACC | ENSG00000198502 | HLA-DRB5 | Chemokine Receptors | 1.555e-03 | 4.147e-03 | 0.6079 | 0.9969 | protective | details |
| ACC | ENSG00000198502 | HLA-DRB5 | Cytokine Receptors | 1.253e-03 | 4.147e-03 | 0.4066 | 0.9975 | protective | details |
| ACC | ENSG00000198502 | HLA-DRB5 | Natural Killer Cell ... | 1.370e-03 | 4.147e-03 | 0.5564 | 0.9973 | protective | details |
| ACC | ENSG00000198502 | HLA-DRB5 | TCR signaling Pathwa... | 1.431e-03 | 4.147e-03 | 0.5718 | 0.9971 | protective | details |
| ACC | ENSG00000157227 | MMP14 | Antigen Processing a... | 1.821e-03 | 2.914e-02 | -0.4443 | -0.9964 | risk | details |
| ACC | ENSG00000135679 | MDM2 | Natural Killer Cell ... | 1.992e-03 | 2.129e-02 | 0.4517 | 0.996 | protective | details |
| ACC | ENSG00000152944 | MED21 | Antigen Processing a... | 1.368e-03 | 2.189e-02 | 0.5093 | 0.9973 | protective | details |
| ACC | ENSG00000166579 | NDEL1 | Natural Killer Cell ... | 1.618e-03 | 2.589e-02 | -0.461 | -0.9968 | risk | details |
| ACC | ENSG00000171862 | PTEN | Antigen Processing a... | 1.534e-03 | 2.454e-02 | -0.5476 | -0.9969 | risk | details |
| ACC | ENSG00000114554 | PLXNA1 | Antigen Processing a... | 1.789e-03 | 2.862e-02 | -0.4941 | -0.9964 | risk | details |
| ACC | ENSG00000115350 | POLE4 | TCR signaling Pathwa... | 1.789e-03 | 2.862e-02 | -0.4634 | -0.9964 | risk | details |
| ACC | ENSG00000221823 | PPP3R1 | Natural Killer Cell ... | 1.515e-03 | 2.424e-02 | -0.4694 | -0.997 | risk | details |