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TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| ACC | ENSG00000079337 | RAPGEF3 | Cytokine Receptors | 1.171e-03 | 1.874e-02 | 0.436 | 0.9977 | protective | details |
| ACC | ENSG00000048649 | RSF1 | Antimicrobials | 1.072e-03 | 1.715e-02 | -0.3685 | -0.9979 | risk | details |
| ACC | ENSG00000240771 | ARHGEF25 | TGFb Family Member | 2.370e-03 | 3.791e-02 | 0.6462 | 0.9953 | risk | details |
| ACC | ENSG00000124226 | RNF114 | Antigen Processing a... | 1.263e-03 | 6.999e-03 | 0.5822 | 0.9975 | protective | details |
| ACC | ENSG00000124226 | RNF114 | Natural Killer Cell ... | 1.263e-03 | 6.999e-03 | 0.512 | 0.9975 | protective | details |
| ACC | ENSG00000124226 | RNF114 | TCR signaling Pathwa... | 1.312e-03 | 6.999e-03 | 0.5182 | 0.9974 | protective | details |
| ACC | ENSG00000151692 | RNF144A | Antigen Processing a... | 1.490e-03 | 2.385e-02 | -0.5191 | -0.997 | risk | details |
| ACC | ENSG00000105705 | SUGP1 | Natural Killer Cell ... | 1.815e-03 | 2.904e-02 | -0.3919 | -0.9964 | risk | details |
| ACC | ENSG00000160949 | TONSL | Antigen Processing a... | 1.927e-03 | 3.083e-02 | -0.4714 | -0.9961 | risk | details |
| ACC | ENSG00000100106 | TRIOBP | TCR signaling Pathwa... | 1.718e-03 | 2.749e-02 | -0.4617 | -0.9966 | risk | details |
| ACC | ENSG00000112343 | TRIM38 | Antigen Processing a... | 1.862e-03 | 7.449e-03 | 0.6333 | 0.9963 | protective | details |
| ACC | ENSG00000112343 | TRIM38 | Antimicrobials | 1.730e-03 | 7.449e-03 | 0.4039 | 0.9965 | protective | details |
| ACC | ENSG00000112343 | TRIM38 | Cytokine Receptors | 1.742e-03 | 7.449e-03 | 0.4011 | 0.9965 | protective | details |
| ACC | ENSG00000112343 | TRIM38 | Interleukins Recepto... | 1.848e-03 | 7.449e-03 | 0.5883 | 0.9963 | protective | details |
| ACC | ENSG00000168883 | USP39 | Chemokine Receptors | 1.456e-03 | 1.164e-02 | -0.644 | -0.9971 | risk | details |
| ACC | ENSG00000168883 | USP39 | Cytokine Receptors | 1.117e-03 | 1.164e-02 | -0.4072 | -0.9978 | risk | details |
| ACC | ENSG00000147394 | ZNF185 | Natural Killer Cell ... | 1.629e-03 | 1.351e-02 | 0.466 | 0.9967 | protective | details |
| ACC | ENSG00000147394 | ZNF185 | TCR signaling Pathwa... | 1.689e-03 | 1.351e-02 | 0.5033 | 0.9966 | protective | details |
| ACC | ENSG00000146007 | ZMAT2 | Antigen Processing a... | 1.429e-03 | 2.286e-02 | 0.5853 | 0.9971 | protective | details |
| ACC | ENSG00000268041 | ERFL | Antigen Processing a... | 2.398e-03 | 3.113e-02 | -0.589 | -0.9952 | risk | details |