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TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| ACC | ENSG00000015479 | MATR3 | TCR signaling Pathwa... | 1.618e-03 | 2.589e-02 | 0.4863 | 0.9968 | protective | details |
| BLCA | ENSG00000157613 | CREB3L1 | Chemokines | 2.205e-03 | 1.083e-02 | 0.5248 | 0.9956 | risk | details |
| BLCA | ENSG00000157613 | CREB3L1 | Cytokines | 1.007e-03 | 8.656e-03 | 0.506 | 0.998 | risk | details |
| BLCA | ENSG00000157613 | CREB3L1 | Cytokine Receptors | 1.018e-03 | 8.656e-03 | 0.4752 | 0.998 | risk | details |
| BLCA | ENSG00000043355 | ZIC2 | Antimicrobials | 1.572e-03 | 8.095e-03 | 0.3287 | 0.9969 | risk | details |
| BLCA | ENSG00000043355 | ZIC2 | Cytokines | 1.595e-03 | 8.095e-03 | 0.3723 | 0.9968 | risk | details |
| BLCA | ENSG00000043355 | ZIC2 | Interleukins Recepto... | 1.905e-03 | 8.095e-03 | 0.6541 | 0.9962 | risk | details |
| BLCA | ENSG00000043355 | ZIC2 | Natural Killer Cell ... | 1.736e-03 | 8.095e-03 | 0.4491 | 0.9965 | risk | details |
| BLCA | ENSG00000167380 | ZNF226 | Antigen Processing a... | 2.331e-03 | 2.515e-02 | -0.464 | -0.9953 | protective | details |
| BLCA | ENSG00000198482 | ZNF808 | Antigen Processing a... | 2.193e-03 | 3.728e-02 | -0.5386 | -0.9956 | protective | details |
| BLCA | ENSG00000113580 | NR3C1 | Antigen Processing a... | 2.268e-03 | 8.213e-03 | 0.4608 | 0.9955 | risk | details |
| BLCA | ENSG00000113580 | NR3C1 | Antimicrobials | 2.415e-03 | 8.213e-03 | 0.2848 | 0.9952 | risk | details |
| BLCA | ENSG00000113580 | NR3C1 | Interleukins Recepto... | 2.151e-03 | 8.213e-03 | 0.4958 | 0.9957 | risk | details |
| BLCA | ENSG00000113580 | NR3C1 | Natural Killer Cell ... | 2.237e-03 | 8.213e-03 | 0.4387 | 0.9955 | risk | details |
| BLCA | ENSG00000113580 | NR3C1 | TCR signaling Pathwa... | 2.237e-03 | 8.213e-03 | 0.3909 | 0.9955 | risk | details |
| BLCA | ENSG00000185591 | SP1 | TCR signaling Pathwa... | 2.353e-03 | 4.000e-02 | 0.4235 | 0.9953 | protective | details |
| BLCA | ENSG00000267680 | ZNF224 | Antigen Processing a... | 2.268e-03 | 1.927e-02 | -0.4961 | -0.9955 | protective | details |
| BLCA | ENSG00000267680 | ZNF224 | Chemokines | 2.268e-03 | 1.927e-02 | -0.3532 | -0.9955 | protective | details |
| BLCA | ENSG00000251192 | ZNF674 | Antigen Processing a... | 1.866e-03 | 3.108e-02 | -0.4638 | -0.9963 | protective | details |
| BLCA | ENSG00000184937 | WT1 | Cytokines | 1.004e-03 | 1.707e-02 | 0.3873 | 0.998 | risk | details |