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TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| BLCA | ENSG00000106459 | NRF1 | Antigen Processing a... | 2.045e-03 | 6.953e-03 | -0.552 | -0.9959 | protective | details |
| BLCA | ENSG00000106459 | NRF1 | Antimicrobials | 1.984e-03 | 6.953e-03 | -0.4142 | -0.996 | protective | details |
| BLCA | ENSG00000106459 | NRF1 | Chemokines | 2.020e-03 | 6.953e-03 | -0.4628 | -0.996 | protective | details |
| BLCA | ENSG00000106459 | NRF1 | Cytokines | 1.965e-03 | 6.953e-03 | -0.361 | -0.9961 | protective | details |
| BLCA | ENSG00000106459 | NRF1 | Interleukins | 2.012e-03 | 6.953e-03 | -0.6414 | -0.996 | protective | details |
| BLCA | ENSG00000016082 | ISL1 | Cytokines | 9.990e-04 | 1.030e-02 | 0.4445 | 0.998 | risk | details |
| BLCA | ENSG00000016082 | ISL1 | TGFb Family Member | 1.212e-03 | 1.030e-02 | 0.7251 | 0.9976 | risk | details |
| BLCA | ENSG00000167232 | ZNF91 | Antigen Processing a... | 2.247e-03 | 1.910e-02 | -0.553 | -0.9955 | protective | details |
| BLCA | ENSG00000167232 | ZNF91 | Natural Killer Cell ... | 2.237e-03 | 1.910e-02 | -0.3526 | -0.9955 | protective | details |
| BLCA | ENSG00000184436 | THAP7 | TCR signaling Pathwa... | 2.183e-03 | 3.712e-02 | -0.4732 | -0.9956 | protective | details |
| BLCA | ENSG00000092203 | TOX4 | Antigen Processing a... | 2.475e-03 | 4.126e-02 | 0.4583 | 0.995 | risk | details |
| BLCA | ENSG00000111145 | ELK3 | Antigen Processing a... | 2.141e-03 | 7.692e-03 | 0.3818 | 0.9957 | risk | details |
| BLCA | ENSG00000111145 | ELK3 | Antimicrobials | 2.227e-03 | 7.692e-03 | 0.3471 | 0.9955 | risk | details |
| BLCA | ENSG00000111145 | ELK3 | Cytokines | 2.262e-03 | 7.692e-03 | 0.2788 | 0.9955 | risk | details |
| BLCA | ENSG00000111145 | ELK3 | Cytokine Receptors | 2.247e-03 | 7.692e-03 | 0.3053 | 0.9955 | risk | details |
| BLCA | ENSG00000111145 | ELK3 | Interleukins Recepto... | 2.083e-03 | 7.692e-03 | 0.4741 | 0.9958 | risk | details |
| BLCA | ENSG00000159885 | ZNF222 | Antigen Processing a... | 2.208e-03 | 2.063e-02 | -0.5228 | -0.9956 | protective | details |
| BLCA | ENSG00000159885 | ZNF222 | Antimicrobials | 2.427e-03 | 2.063e-02 | -0.3139 | -0.9951 | protective | details |
| BLCA | ENSG00000136826 | KLF4 | Interleukins Recepto... | 2.469e-03 | 7.562e-03 | 0.617 | 0.9951 | risk | details |
| BLCA | ENSG00000117625 | RCOR3 | Antigen Processing a... | 2.227e-03 | 1.309e-02 | -0.4736 | -0.9955 | protective | details |