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TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| ACC | ENSG00000171161 | ZNF672 | TCR signaling Pathwa... | 1.949e-03 | 1.040e-02 | -0.4654 | -0.9961 | risk | details |
| ACC | ENSG00000105392 | CRX | Natural Killer Cell ... | 2.092e-03 | 3.347e-02 | -0.4369 | -0.9958 | risk | details |
| ACC | ENSG00000136574 | GATA4 | Chemokines | 2.252e-03 | 1.347e-02 | 0.4413 | 0.9955 | risk | details |
| ACC | ENSG00000136574 | GATA4 | TGFb Family Member | 2.208e-03 | 1.347e-02 | 0.6684 | 0.9956 | risk | details |
| ACC | ENSG00000172216 | CEBPB | Antigen Processing a... | 1.938e-03 | 1.067e-02 | 0.5731 | 0.9961 | protective | details |
| ACC | ENSG00000172216 | CEBPB | Antimicrobials | 1.938e-03 | 1.067e-02 | 0.3487 | 0.9961 | protective | details |
| ACC | ENSG00000172216 | CEBPB | Interleukins Recepto... | 2.000e-03 | 1.067e-02 | 0.5337 | 0.996 | protective | details |
| ACC | ENSG00000168610 | STAT3 | Antimicrobials | 2.110e-03 | 3.376e-02 | 0.3252 | 0.9958 | protective | details |
| ACC | ENSG00000125347 | IRF1 | Antigen Processing a... | 1.541e-03 | 6.240e-03 | 0.6365 | 0.9969 | protective | details |
| ACC | ENSG00000125347 | IRF1 | Antimicrobials | 1.366e-03 | 6.240e-03 | 0.486 | 0.9973 | protective | details |
| ACC | ENSG00000125347 | IRF1 | Natural Killer Cell ... | 1.541e-03 | 6.240e-03 | 0.5553 | 0.9969 | protective | details |
| ACC | ENSG00000125347 | IRF1 | TCR signaling Pathwa... | 1.560e-03 | 6.240e-03 | 0.567 | 0.9969 | protective | details |
| ACC | ENSG00000117625 | RCOR3 | Antigen Processing a... | 1.776e-03 | 2.842e-02 | -0.4887 | -0.9964 | risk | details |
| ACC | ENSG00000173153 | ESRRA | Cytokines | 2.433e-03 | 2.837e-02 | -0.3739 | -0.9951 | protective | details |
| ACC | ENSG00000107249 | GLIS3 | Cytokine Receptors | 1.445e-03 | 1.619e-02 | 0.3889 | 0.9971 | protective | details |
| ACC | ENSG00000162714 | ZNF496 | Natural Killer Cell ... | 1.678e-03 | 2.685e-02 | -0.4023 | -0.9966 | risk | details |
| ACC | ENSG00000148737 | TCF7L2 | Antigen Processing a... | 1.499e-03 | 1.199e-02 | -0.4876 | -0.997 | risk | details |
| ACC | ENSG00000148737 | TCF7L2 | Antimicrobials | 1.326e-03 | 1.199e-02 | -0.3409 | -0.9973 | risk | details |
| ACC | ENSG00000116990 | MYCL | Antimicrobials | 1.112e-03 | 7.027e-03 | 0.3961 | 0.9978 | protective | details |
| ACC | ENSG00000116990 | MYCL | Cytokine Receptors | 1.174e-03 | 7.027e-03 | 0.4363 | 0.9977 | protective | details |