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TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| BLCA | ENSG00000115738 | ID2 | Natural Killer Cell ... | 2.463e-03 | 8.651e-03 | -0.4127 | -0.9951 | protective | details |
| BLCA | ENSG00000198464 | ZNF480 | Antigen Processing a... | 2.273e-03 | 2.068e-02 | -0.5003 | -0.9955 | protective | details |
| BLCA | ENSG00000198464 | ZNF480 | Antimicrobials | 2.433e-03 | 2.068e-02 | -0.2914 | -0.9951 | protective | details |
| BLCA | ENSG00000196460 | RFX8 | Chemokines | 1.225e-03 | 1.042e-02 | 0.4623 | 0.9975 | risk | details |
| BLCA | ENSG00000196460 | RFX8 | Cytokines | 1.064e-03 | 1.042e-02 | 0.4007 | 0.9979 | risk | details |
| BLCA | ENSG00000196233 | LCOR | Antigen Processing a... | 1.883e-03 | 3.202e-02 | -0.4187 | -0.9962 | protective | details |
| BLCA | ENSG00000142556 | ZNF614 | Antigen Processing a... | 2.012e-03 | 3.421e-02 | -0.4955 | -0.996 | protective | details |
| BLCA | ENSG00000197044 | ZNF441 | Antigen Processing a... | 2.336e-03 | 1.544e-02 | -0.5325 | -0.9953 | protective | details |
| BLCA | ENSG00000197044 | ZNF441 | Natural Killer Cell ... | 2.315e-03 | 1.544e-02 | -0.3335 | -0.9954 | protective | details |
| BLCA | ENSG00000116132 | PRRX1 | Cytokines | 1.142e-03 | 1.320e-02 | 0.3936 | 0.9977 | risk | details |
| BLCA | ENSG00000116132 | PRRX1 | Cytokine Receptors | 2.418e-03 | 1.370e-02 | 0.3575 | 0.9952 | risk | details |
| BLCA | ENSG00000116132 | PRRX1 | TGFb Family Member | 1.553e-03 | 1.320e-02 | 0.5835 | 0.9969 | risk | details |
| BLCA | ENSG00000176371 | ZSCAN2 | Interleukins Recepto... | 2.457e-03 | 1.476e-02 | -0.5221 | -0.9951 | protective | details |
| BLCA | ENSG00000178860 | MSC | Antimicrobials | 1.005e-03 | 4.398e-03 | 0.4233 | 0.998 | risk | details |
| BLCA | ENSG00000178860 | MSC | Chemokines | 1.125e-03 | 4.398e-03 | 0.6335 | 0.9978 | risk | details |
| BLCA | ENSG00000178860 | MSC | Cytokines | 1.007e-03 | 4.398e-03 | 0.587 | 0.998 | risk | details |
| BLCA | ENSG00000178860 | MSC | Cytokine Receptors | 1.025e-03 | 4.398e-03 | 0.489 | 0.998 | risk | details |
| BLCA | ENSG00000178860 | MSC | TGFb Family Member | 1.294e-03 | 4.398e-03 | 0.7084 | 0.9974 | risk | details |
| BLCA | ENSG00000167785 | ZNF558 | Antigen Processing a... | 2.033e-03 | 1.185e-02 | -0.5695 | -0.9959 | protective | details |
| BLCA | ENSG00000167785 | ZNF558 | Antimicrobials | 2.075e-03 | 1.185e-02 | -0.3253 | -0.9959 | protective | details |