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TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| BLCA | ENSG00000167785 | ZNF558 | Chemokines | 2.092e-03 | 1.185e-02 | -0.4468 | -0.9958 | protective | details |
| BLCA | ENSG00000176692 | FOXC2 | Cytokines | 1.041e-03 | 8.213e-03 | 0.4582 | 0.9979 | risk | details |
| BLCA | ENSG00000176692 | FOXC2 | Cytokine Receptors | 1.080e-03 | 8.213e-03 | 0.4498 | 0.9978 | risk | details |
| BLCA | ENSG00000176692 | FOXC2 | TGFb Family Member | 1.449e-03 | 8.213e-03 | 0.6965 | 0.9971 | risk | details |
| BLCA | ENSG00000197857 | ZNF44 | Antigen Processing a... | 2.336e-03 | 1.118e-02 | -0.5536 | -0.9953 | protective | details |
| BLCA | ENSG00000197857 | ZNF44 | Chemokines | 2.326e-03 | 1.118e-02 | -0.3573 | -0.9953 | protective | details |
| BLCA | ENSG00000197857 | ZNF44 | Natural Killer Cell ... | 2.347e-03 | 1.118e-02 | -0.357 | -0.9953 | protective | details |
| BLCA | ENSG00000162599 | NFIA | Cytokine Receptors | 1.536e-03 | 1.458e-02 | 0.3389 | 0.9969 | risk | details |
| BLCA | ENSG00000162599 | NFIA | Interleukins Recepto... | 1.715e-03 | 1.458e-02 | 0.5491 | 0.9966 | risk | details |
| BLCA | ENSG00000171532 | NEUROD2 | Cytokines | 1.052e-03 | 1.788e-02 | 0.3878 | 0.9979 | protective | details |
| BLCA | ENSG00000161914 | ZNF653 | TCR signaling Pathwa... | 2.105e-03 | 3.579e-02 | -0.3865 | -0.9958 | protective | details |
| BLCA | ENSG00000091656 | ZFHX4 | Cytokines | 1.086e-03 | 1.846e-02 | 0.3709 | 0.9978 | risk | details |
| BLCA | ENSG00000010030 | ETV7 | TGFb Family Member | 1.748e-03 | 1.027e-02 | -0.638 | -0.9965 | protective | details |
| BLCA | ENSG00000249709 | ZNF564 | Antigen Processing a... | 2.288e-03 | 1.324e-02 | -0.5873 | -0.9954 | protective | details |
| BLCA | ENSG00000249709 | ZNF564 | Antimicrobials | 2.336e-03 | 1.324e-02 | -0.2966 | -0.9953 | protective | details |
| BLCA | ENSG00000249709 | ZNF564 | Cytokines | 2.331e-03 | 1.324e-02 | -0.2648 | -0.9953 | protective | details |
| BLCA | ENSG00000069812 | HES2 | Antigen Processing a... | 1.538e-03 | 4.180e-03 | 0.4807 | 0.9969 | risk | details |
| BLCA | ENSG00000069812 | HES2 | Antimicrobials | 1.328e-03 | 4.180e-03 | 0.4239 | 0.9973 | risk | details |
| BLCA | ENSG00000069812 | HES2 | Chemokines | 1.546e-03 | 4.180e-03 | 0.4734 | 0.9969 | risk | details |
| BLCA | ENSG00000069812 | HES2 | Cytokines | 1.316e-03 | 4.180e-03 | 0.4006 | 0.9974 | risk | details |