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TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| BLCA | ENSG00000069812 | HES2 | Interleukins | 1.721e-03 | 4.180e-03 | 0.6009 | 0.9966 | risk | details |
| BLCA | ENSG00000069812 | HES2 | Interleukins Recepto... | 1.664e-03 | 4.180e-03 | 0.4884 | 0.9967 | risk | details |
| BLCA | ENSG00000069812 | HES2 | Natural Killer Cell ... | 1.520e-03 | 4.180e-03 | 0.4358 | 0.997 | risk | details |
| BLCA | ENSG00000213928 | IRF9 | Antigen Processing a... | 1.570e-03 | 6.933e-03 | 0.4723 | 0.9969 | protective | details |
| BLCA | ENSG00000213928 | IRF9 | Antimicrobials | 1.359e-03 | 6.933e-03 | 0.3467 | 0.9973 | protective | details |
| BLCA | ENSG00000213928 | IRF9 | Natural Killer Cell ... | 1.575e-03 | 6.933e-03 | 0.5301 | 0.9969 | protective | details |
| BLCA | ENSG00000213928 | IRF9 | TCR signaling Pathwa... | 1.631e-03 | 6.933e-03 | 0.5728 | 0.9967 | protective | details |
| BLCA | ENSG00000132170 | PPARG | Antigen Processing a... | 2.212e-03 | 2.544e-02 | -0.4683 | -0.9956 | protective | details |
| BLCA | ENSG00000130818 | ZNF426 | Antigen Processing a... | 1.821e-03 | 9.239e-03 | -0.6056 | -0.9964 | protective | details |
| BLCA | ENSG00000130818 | ZNF426 | Antimicrobials | 1.721e-03 | 9.239e-03 | -0.3368 | -0.9966 | protective | details |
| BLCA | ENSG00000130818 | ZNF426 | Chemokines | 1.852e-03 | 9.239e-03 | -0.4554 | -0.9963 | protective | details |
| BLCA | ENSG00000130818 | ZNF426 | TGFb Family Member R... | 2.174e-03 | 9.239e-03 | 0.7998 | 0.9957 | protective | details |
| BLCA | ENSG00000164107 | HAND2 | Cytokines | 1.007e-03 | 1.079e-02 | 0.4495 | 0.998 | risk | details |
| BLCA | ENSG00000164107 | HAND2 | TGFb Family Member | 1.269e-03 | 1.079e-02 | 0.6593 | 0.9975 | risk | details |
| BLCA | ENSG00000104447 | TRPS1 | Cytokines | 1.323e-03 | 1.177e-02 | 0.3242 | 0.9974 | risk | details |
| BLCA | ENSG00000104447 | TRPS1 | Cytokine Receptors | 1.385e-03 | 1.177e-02 | 0.3535 | 0.9972 | risk | details |
| BLCA | ENSG00000204611 | ZNF616 | Antigen Processing a... | 2.083e-03 | 9.004e-03 | -0.5652 | -0.9958 | protective | details |
| BLCA | ENSG00000204611 | ZNF616 | Antimicrobials | 1.996e-03 | 9.004e-03 | -0.3243 | -0.996 | protective | details |
| BLCA | ENSG00000204611 | ZNF616 | Chemokines | 2.088e-03 | 9.004e-03 | -0.3897 | -0.9958 | protective | details |
| BLCA | ENSG00000204611 | ZNF616 | Natural Killer Cell ... | 2.119e-03 | 9.004e-03 | -0.3807 | -0.9958 | protective | details |