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TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| BLCA | ENSG00000182903 | ZNF721 | Antigen Processing a... | 2.165e-03 | 1.840e-02 | -0.5269 | -0.9957 | protective | details |
| BLCA | ENSG00000182903 | ZNF721 | Interleukins Recepto... | 2.132e-03 | 1.840e-02 | -0.4974 | -0.9957 | protective | details |
| BLCA | ENSG00000083828 | ZNF586 | Antigen Processing a... | 1.908e-03 | 3.220e-02 | -0.4679 | -0.9962 | protective | details |
| BLCA | ENSG00000196275 | GTF2IRD2 | Interleukins Recepto... | 2.451e-03 | 1.145e-02 | -0.4073 | -0.9951 | protective | details |
| BLCA | ENSG00000099326 | MZF1 | Antigen Processing a... | 2.174e-03 | 3.696e-02 | -0.3784 | -0.9957 | protective | details |
| BLCA | ENSG00000170485 | NPAS2 | Antigen Processing a... | 2.083e-03 | 3.542e-02 | -0.4761 | -0.9958 | protective | details |
| BLCA | ENSG00000131196 | NFATC1 | Chemokines | 1.076e-03 | 6.100e-03 | 0.5386 | 0.9978 | risk | details |
| BLCA | ENSG00000131196 | NFATC1 | Cytokines | 1.000e-03 | 6.100e-03 | 0.5187 | 0.998 | risk | details |
| BLCA | ENSG00000131196 | NFATC1 | Cytokine Receptors | 1.014e-03 | 6.100e-03 | 0.577 | 0.998 | risk | details |
| BLCA | ENSG00000171443 | ZNF524 | TCR signaling Pathwa... | 2.070e-03 | 3.520e-02 | -0.3864 | -0.9959 | protective | details |
| BLCA | ENSG00000064933 | PMS1 | Antigen Processing a... | 2.375e-03 | 1.548e-02 | -0.576 | -0.9952 | protective | details |
| BLCA | ENSG00000169946 | ZFPM2 | Cytokines | 1.232e-03 | 1.345e-02 | 0.4008 | 0.9975 | risk | details |
| BLCA | ENSG00000169946 | ZFPM2 | TGFb Family Member | 1.582e-03 | 1.345e-02 | 0.7179 | 0.9968 | risk | details |
| BLCA | ENSG00000129173 | E2F8 | Cytokines | 1.931e-03 | 3.282e-02 | -0.3263 | -0.9961 | protective | details |
| BLCA | ENSG00000141027 | NCOR1 | Antigen Processing a... | 1.493e-03 | 2.537e-02 | -0.4183 | -0.997 | risk | details |
| BLCA | ENSG00000103460 | TOX3 | Interleukins Recepto... | 2.427e-03 | 1.782e-02 | -0.4564 | -0.9951 | protective | details |
| BLCA | ENSG00000256683 | ZNF350 | Antigen Processing a... | 2.237e-03 | 3.803e-02 | -0.4692 | -0.9955 | protective | details |
| BLCA | ENSG00000011590 | ZBTB32 | TCR signaling Pathwa... | 1.297e-03 | 2.205e-02 | 0.512 | 0.9974 | protective | details |
| BLCA | ENSG00000189180 | ZNF33A | Antigen Processing a... | 2.427e-03 | 1.662e-02 | -0.5339 | -0.9951 | protective | details |
| BLCA | ENSG00000189180 | ZNF33A | Natural Killer Cell ... | 2.404e-03 | 1.662e-02 | -0.3449 | -0.9952 | protective | details |