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TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| BLCA | ENSG00000174332 | GLIS1 | Cytokines | 9.990e-04 | 1.698e-02 | 0.4995 | 0.998 | risk | details |
| BLCA | ENSG00000089225 | TBX5 | Chemokines | 2.053e-03 | 1.164e-02 | 0.4875 | 0.9959 | risk | details |
| BLCA | ENSG00000089225 | TBX5 | Cytokines | 9.990e-04 | 9.861e-03 | 0.4719 | 0.998 | risk | details |
| BLCA | ENSG00000089225 | TBX5 | TGFb Family Member | 1.160e-03 | 9.861e-03 | 0.723 | 0.9977 | risk | details |
| BLCA | ENSG00000095574 | IKZF5 | Antigen Processing a... | 1.773e-03 | 1.985e-02 | -0.6013 | -0.9965 | protective | details |
| BLCA | ENSG00000177374 | HIC1 | Cytokines | 1.117e-03 | 8.612e-03 | 0.4607 | 0.9978 | risk | details |
| BLCA | ENSG00000177374 | HIC1 | Cytokine Receptors | 1.198e-03 | 8.612e-03 | 0.4458 | 0.9976 | risk | details |
| BLCA | ENSG00000177374 | HIC1 | TGFb Family Member | 1.520e-03 | 8.612e-03 | 0.69 | 0.997 | risk | details |
| BLCA | ENSG00000196267 | ZNF836 | Antigen Processing a... | 2.398e-03 | 2.361e-02 | -0.5875 | -0.9952 | protective | details |
| BLCA | ENSG00000135111 | TBX3 | Antigen Processing a... | 2.404e-03 | 4.087e-02 | -0.4275 | -0.9952 | protective | details |
| BLCA | ENSG00000137834 | SMAD6 | Antigen Processing a... | 2.033e-03 | 9.219e-03 | -0.4977 | -0.9959 | protective | details |
| BLCA | ENSG00000137834 | SMAD6 | Antimicrobials | 2.169e-03 | 9.219e-03 | -0.2802 | -0.9957 | protective | details |
| BLCA | ENSG00000137834 | SMAD6 | Interleukins Recepto... | 1.984e-03 | 9.219e-03 | -0.4923 | -0.996 | protective | details |
| BLCA | ENSG00000137834 | SMAD6 | Natural Killer Cell ... | 2.024e-03 | 9.219e-03 | -0.3469 | -0.996 | protective | details |
| BLCA | ENSG00000096654 | ZNF184 | Antimicrobials | 2.392e-03 | 4.067e-02 | -0.3001 | -0.9952 | protective | details |
| BLCA | ENSG00000116809 | ZBTB17 | Chemokine Receptors | 2.179e-03 | 2.048e-02 | -0.5113 | -0.9956 | protective | details |
| BLCA | ENSG00000116809 | ZBTB17 | Cytokine Receptors | 2.410e-03 | 2.048e-02 | -0.3267 | -0.9952 | protective | details |
| BLCA | ENSG00000170949 | ZNF160 | Antigen Processing a... | 2.294e-03 | 2.291e-02 | -0.5718 | -0.9954 | protective | details |
| BLCA | ENSG00000154727 | GABPA | Antigen Processing a... | 1.905e-03 | 3.238e-02 | -0.5126 | -0.9962 | protective | details |
| BLCA | ENSG00000142065 | ZFP14 | Antigen Processing a... | 2.451e-03 | 1.152e-02 | -0.5408 | -0.9951 | protective | details |