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TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| BLCA | ENSG00000187837 | H1-2 | Natural Killer Cell ... | 2.294e-03 | 1.950e-02 | -0.4403 | -0.9954 | protective | details |
| BLCA | ENSG00000198625 | MDM4 | Antigen Processing a... | 2.242e-03 | 1.303e-02 | -0.4904 | -0.9955 | protective | details |
| BLCA | ENSG00000198625 | MDM4 | Antimicrobials | 2.183e-03 | 1.303e-02 | -0.2987 | -0.9956 | protective | details |
| BLCA | ENSG00000198625 | MDM4 | Chemokines | 2.299e-03 | 1.303e-02 | -0.3628 | -0.9954 | protective | details |
| BLCA | ENSG00000275023 | MLLT6 | Antigen Processing a... | 2.257e-03 | 3.837e-02 | -0.4362 | -0.9955 | protective | details |
| BLCA | ENSG00000186310 | NAP1L3 | Cytokines | 2.008e-03 | 1.707e-02 | 0.3746 | 0.996 | risk | details |
| BLCA | ENSG00000186310 | NAP1L3 | TGFb Family Member | 1.307e-03 | 1.707e-02 | 0.6729 | 0.9974 | risk | details |
| BLCA | ENSG00000134250 | NOTCH2 | Cytokine Receptors | 2.119e-03 | 3.602e-02 | 0.2812 | 0.9958 | risk | details |
| BLCA | ENSG00000197724 | PHF2 | Antigen Processing a... | 1.869e-03 | 1.129e-02 | -0.4241 | -0.9963 | risk | details |
| BLCA | ENSG00000197724 | PHF2 | Cytokine Receptors | 1.992e-03 | 1.129e-02 | 0.2977 | 0.996 | risk | details |
| BLCA | ENSG00000197724 | PHF2 | TCR signaling Pathwa... | 1.992e-03 | 1.129e-02 | 0.4278 | 0.996 | risk | details |
| BLCA | ENSG00000162521 | RBBP4 | Interleukins Recepto... | 2.299e-03 | 1.749e-02 | -0.5517 | -0.9954 | protective | details |
| BLCA | ENSG00000197780 | TAF13 | Antigen Processing a... | 2.404e-03 | 3.761e-02 | 0.3691 | 0.9952 | risk | details |
| BLCA | ENSG00000140682 | TGFB1I1 | Cytokines | 1.178e-03 | 1.264e-02 | 0.4429 | 0.9976 | risk | details |
| BLCA | ENSG00000140682 | TGFB1I1 | TGFb Family Member | 1.661e-03 | 1.264e-02 | 0.6337 | 0.9967 | risk | details |
| BLCA | ENSG00000151923 | TIAL1 | Antigen Processing a... | 1.842e-03 | 1.565e-02 | -0.5136 | -0.9963 | protective | details |
| BLCA | ENSG00000151923 | TIAL1 | Antimicrobials | 1.767e-03 | 1.565e-02 | -0.3529 | -0.9965 | protective | details |
| BLCA | ENSG00000134086 | VHL | Antigen Processing a... | 2.188e-03 | 1.427e-02 | -0.5153 | -0.9956 | protective | details |
| BLCA | ENSG00000134086 | VHL | TCR signaling Pathwa... | 1.821e-03 | 1.427e-02 | 0.3905 | 0.9964 | protective | details |
| BLCA | ENSG00000154767 | XPC | Antigen Processing a... | 1.992e-03 | 1.145e-02 | -0.5356 | -0.996 | protective | details |