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TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| BLCA | ENSG00000154767 | XPC | Antimicrobials | 1.931e-03 | 1.145e-02 | -0.2875 | -0.9961 | protective | details |
| BLCA | ENSG00000154767 | XPC | Natural Killer Cell ... | 2.020e-03 | 1.145e-02 | -0.4016 | -0.996 | protective | details |
| BLCA | ENSG00000128016 | ZFP36 | Antimicrobials | 1.577e-03 | 6.273e-03 | 0.4574 | 0.9968 | risk | details |
| BLCA | ENSG00000128016 | ZFP36 | Chemokines | 1.779e-03 | 6.273e-03 | 0.5346 | 0.9964 | risk | details |
| BLCA | ENSG00000128016 | ZFP36 | Cytokines | 1.565e-03 | 6.273e-03 | 0.4638 | 0.9969 | risk | details |
| BLCA | ENSG00000128016 | ZFP36 | Cytokine Receptors | 1.639e-03 | 6.273e-03 | 0.4619 | 0.9967 | risk | details |
| BLCA | ENSG00000128016 | ZFP36 | Interleukins | 1.845e-03 | 6.273e-03 | 0.6534 | 0.9963 | risk | details |
| BLCA | ENSG00000159388 | BTG2 | Antigen Processing a... | 2.336e-03 | 1.986e-02 | -0.3684 | -0.9953 | protective | details |
| BLCA | ENSG00000159388 | BTG2 | Interleukins Recepto... | 2.247e-03 | 1.986e-02 | -0.4821 | -0.9955 | protective | details |
| BLCA | ENSG00000074266 | EED | Antigen Processing a... | 2.309e-03 | 9.815e-03 | 0.6137 | 0.9954 | protective | details |
| BLCA | ENSG00000074266 | EED | Cytokines | 1.686e-03 | 9.815e-03 | -0.3345 | -0.9966 | protective | details |
| BLCA | ENSG00000074266 | EED | Cytokine Receptors | 1.757e-03 | 9.815e-03 | -0.3891 | -0.9965 | protective | details |
| BLCA | ENSG00000074266 | EED | TGFb Family Member | 1.901e-03 | 9.815e-03 | -0.6341 | -0.9962 | protective | details |
| BLCA | ENSG00000112739 | PRPF4B | Antigen Processing a... | 1.786e-03 | 1.852e-02 | -0.3742 | -0.9964 | protective | details |
| BLCA | ENSG00000112739 | PRPF4B | TCR signaling Pathwa... | 2.179e-03 | 1.852e-02 | 0.4667 | 0.9956 | protective | details |
| BLCA | ENSG00000107164 | FUBP3 | TCR signaling Pathwa... | 2.299e-03 | 3.908e-02 | 0.4032 | 0.9954 | risk | details |
| BLCA | ENSG00000103168 | TAF1C | Antigen Processing a... | 2.227e-03 | 3.786e-02 | -0.4119 | -0.9955 | protective | details |
| BLCA | ENSG00000169744 | LDB2 | TGFb Family Member | 1.642e-03 | 1.328e-02 | 0.6805 | 0.9967 | risk | details |
| BLCA | ENSG00000155508 | CNOT8 | TCR signaling Pathwa... | 2.008e-03 | 3.414e-02 | 0.4656 | 0.996 | protective | details |
| BLCA | ENSG00000112214 | FHL5 | Cytokines | 2.375e-03 | 1.481e-02 | 0.3605 | 0.9952 | risk | details |