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TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| BLCA | ENSG00000018408 | WWTR1 | Cytokines | 1.645e-03 | 1.021e-02 | 0.3711 | 0.9967 | risk | details |
| BLCA | ENSG00000018408 | WWTR1 | Cytokine Receptors | 1.704e-03 | 1.021e-02 | 0.3626 | 0.9966 | risk | details |
| BLCA | ENSG00000275700 | AATF | Antigen Processing a... | 2.247e-03 | 3.820e-02 | 0.5196 | 0.9955 | risk | details |
| BLCA | ENSG00000148677 | ANKRD1 | Cytokines | 1.071e-03 | 1.276e-02 | 0.5128 | 0.9979 | risk | details |
| BLCA | ENSG00000148677 | ANKRD1 | TGFb Family Member | 1.502e-03 | 1.276e-02 | 0.7225 | 0.997 | risk | details |
| BLCA | ENSG00000075292 | ZNF638 | Antigen Processing a... | 2.392e-03 | 4.067e-02 | -0.5348 | -0.9952 | protective | details |
| BLCA | ENSG00000146109 | ABT1 | Antigen Processing a... | 2.083e-03 | 1.771e-02 | 0.4778 | 0.9958 | protective | details |
| BLCA | ENSG00000146109 | ABT1 | Cytokine Receptors | 1.805e-03 | 1.771e-02 | -0.3879 | -0.9964 | protective | details |
| BLCA | ENSG00000066379 | ZNRD1 | Antigen Processing a... | 2.439e-03 | 2.073e-02 | 0.3873 | 0.9951 | protective | details |
| BLCA | ENSG00000066379 | ZNRD1 | Cytokine Receptors | 1.608e-03 | 2.073e-02 | -0.2949 | -0.9968 | protective | details |
| BLCA | ENSG00000088448 | ANKRD10 | Antigen Processing a... | 2.387e-03 | 1.578e-02 | -0.4868 | -0.9952 | protective | details |
| BLCA | ENSG00000088448 | ANKRD10 | Interleukins Recepto... | 2.232e-03 | 1.578e-02 | -0.5031 | -0.9955 | protective | details |
| BLCA | ENSG00000189266 | PNRC2 | Antigen Processing a... | 2.475e-03 | 1.647e-02 | -0.5016 | -0.995 | protective | details |
| BLCA | ENSG00000189266 | PNRC2 | Natural Killer Cell ... | 2.475e-03 | 1.647e-02 | -0.3713 | -0.995 | protective | details |
| BLCA | ENSG00000178585 | CTNNBIP1 | Antimicrobials | 1.695e-03 | 1.441e-02 | 0.3081 | 0.9966 | risk | details |
| BLCA | ENSG00000178585 | CTNNBIP1 | Cytokines | 1.678e-03 | 1.441e-02 | 0.296 | 0.9966 | risk | details |
| BLCA | ENSG00000165671 | NSD1 | TCR signaling Pathwa... | 2.309e-03 | 3.926e-02 | 0.3991 | 0.9954 | risk | details |
| BLCA | ENSG00000136492 | BRIP1 | Antigen Processing a... | 2.320e-03 | 1.972e-02 | 0.3469 | 0.9954 | protective | details |
| BLCA | ENSG00000136492 | BRIP1 | TCR signaling Pathwa... | 2.155e-03 | 1.972e-02 | 0.414 | 0.9957 | protective | details |
| BLCA | ENSG00000083896 | YTHDC1 | Antigen Processing a... | 2.398e-03 | 4.077e-02 | -0.4883 | -0.9952 | protective | details |