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TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| BLCA | ENSG00000197976 | AKAP17A | Antigen Processing a... | 2.299e-03 | 3.908e-02 | -0.4072 | -0.9954 | protective | details |
| BLCA | ENSG00000142192 | APP | Antimicrobials | 1.733e-03 | 8.142e-03 | 0.3112 | 0.9965 | risk | details |
| BLCA | ENSG00000142192 | APP | Chemokines | 1.916e-03 | 8.142e-03 | 0.4361 | 0.9962 | risk | details |
| BLCA | ENSG00000142192 | APP | Cytokines | 1.724e-03 | 8.142e-03 | 0.3264 | 0.9966 | risk | details |
| BLCA | ENSG00000142192 | APP | Cytokine Receptors | 1.779e-03 | 8.142e-03 | 0.3662 | 0.9964 | risk | details |
| BLCA | ENSG00000128335 | APOL2 | Antigen Processing a... | 2.398e-03 | 1.682e-02 | 0.4731 | 0.9952 | protective | details |
| BLCA | ENSG00000128335 | APOL2 | Natural Killer Cell ... | 2.427e-03 | 1.682e-02 | 0.4307 | 0.9951 | protective | details |
| BLCA | ENSG00000124788 | ATXN1 | Cytokine Receptors | 2.398e-03 | 2.009e-02 | 0.3069 | 0.9952 | risk | details |
| BLCA | ENSG00000162650 | ATXN7L2 | Antigen Processing a... | 2.336e-03 | 1.519e-02 | -0.3849 | -0.9953 | protective | details |
| BLCA | ENSG00000162650 | ATXN7L2 | Interleukins Recepto... | 2.242e-03 | 1.519e-02 | -0.4891 | -0.9955 | protective | details |
| BLCA | ENSG00000198691 | ABCA4 | Cytokines | 1.645e-03 | 1.057e-02 | 0.3519 | 0.9967 | risk | details |
| BLCA | ENSG00000198691 | ABCA4 | Cytokine Receptors | 1.698e-03 | 1.057e-02 | 0.3547 | 0.9966 | risk | details |
| BLCA | ENSG00000198691 | ABCA4 | Interleukins Recepto... | 1.866e-03 | 1.057e-02 | 0.5932 | 0.9963 | risk | details |
| BLCA | ENSG00000204256 | BRD2 | Cytokine Receptors | 1.287e-03 | 1.523e-02 | -0.3682 | -0.9974 | protective | details |
| BLCA | ENSG00000170004 | CHD3 | Antigen Processing a... | 2.066e-03 | 3.512e-02 | -0.4148 | -0.9959 | protective | details |
| BLCA | ENSG00000104859 | CLASRP | Cytokine Receptors | 2.217e-03 | 3.769e-02 | -0.2895 | -0.9956 | protective | details |
| BLCA | ENSG00000036257 | CUL3 | TCR signaling Pathwa... | 2.463e-03 | 4.187e-02 | 0.4595 | 0.9951 | risk | details |
| BLCA | ENSG00000082258 | CCNT2 | Antigen Processing a... | 2.151e-03 | 3.656e-02 | -0.4683 | -0.9957 | protective | details |
| BLCA | ENSG00000132964 | CDK8 | Cytokines | 1.506e-03 | 2.560e-02 | 0.3273 | 0.997 | risk | details |
| BLCA | ENSG00000159176 | CSRP1 | Cytokines | 1.248e-03 | 1.056e-02 | 0.4322 | 0.9975 | risk | details |