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TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| BLCA | ENSG00000022267 | FHL1 | TGFb Family Member | 1.299e-03 | 1.104e-02 | 0.6837 | 0.9974 | risk | details |
| BLCA | ENSG00000007237 | AC005747.1 | Chemokines | 1.245e-03 | 6.142e-03 | 0.4652 | 0.9975 | risk | details |
| BLCA | ENSG00000007237 | AC005747.1 | Cytokines | 1.052e-03 | 6.142e-03 | 0.3979 | 0.9979 | risk | details |
| BLCA | ENSG00000007237 | AC005747.1 | Cytokine Receptors | 1.107e-03 | 6.142e-03 | 0.4396 | 0.9978 | risk | details |
| BLCA | ENSG00000007237 | AC005747.1 | TGFb Family Member | 1.445e-03 | 6.142e-03 | 0.6504 | 0.9971 | risk | details |
| BLCA | ENSG00000094631 | HDAC6 | Antigen Processing a... | 2.381e-03 | 2.083e-02 | -0.5286 | -0.9952 | protective | details |
| BLCA | ENSG00000094631 | HDAC6 | Antimicrobials | 2.451e-03 | 2.083e-02 | -0.323 | -0.9951 | protective | details |
| BLCA | ENSG00000146021 | KLHL3 | Antigen Processing a... | 2.433e-03 | 4.136e-02 | -0.4239 | -0.9951 | protective | details |
| BLCA | ENSG00000135686 | KLHL36 | Antigen Processing a... | 1.883e-03 | 3.202e-02 | -0.619 | -0.9962 | protective | details |
| BLCA | ENSG00000102271 | KLHL4 | Cytokines | 1.244e-03 | 1.115e-02 | 0.3214 | 0.9975 | risk | details |
| BLCA | ENSG00000102271 | KLHL4 | Cytokine Receptors | 1.312e-03 | 1.115e-02 | 0.3571 | 0.9974 | risk | details |
| BLCA | ENSG00000109790 | KLHL5 | Antigen Processing a... | 1.845e-03 | 4.707e-03 | 0.3696 | 0.9963 | risk | details |
| BLCA | ENSG00000109790 | KLHL5 | Antimicrobials | 1.828e-03 | 4.707e-03 | 0.2735 | 0.9963 | risk | details |
| BLCA | ENSG00000109790 | KLHL5 | Cytokines | 1.802e-03 | 4.707e-03 | 0.2642 | 0.9964 | risk | details |
| BLCA | ENSG00000109790 | KLHL5 | Cytokine Receptors | 1.898e-03 | 4.707e-03 | 0.3031 | 0.9962 | risk | details |
| BLCA | ENSG00000109790 | KLHL5 | Interleukins Recepto... | 1.938e-03 | 4.707e-03 | 0.4412 | 0.9961 | risk | details |
| BLCA | ENSG00000109790 | KLHL5 | Natural Killer Cell ... | 1.842e-03 | 4.707e-03 | 0.3816 | 0.9963 | risk | details |
| BLCA | ENSG00000109790 | KLHL5 | TCR signaling Pathwa... | 1.894e-03 | 4.707e-03 | 0.4293 | 0.9962 | risk | details |
| BLCA | ENSG00000120049 | KCNIP2 | Antigen Processing a... | 2.392e-03 | 1.296e-02 | -0.6243 | -0.9952 | protective | details |
| BLCA | ENSG00000120049 | KCNIP2 | Interleukins Recepto... | 2.179e-03 | 1.296e-02 | -0.5422 | -0.9956 | protective | details |