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TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| BLCA | ENSG00000120049 | KCNIP2 | Natural Killer Cell ... | 2.381e-03 | 1.296e-02 | -0.4486 | -0.9952 | protective | details |
| BLCA | ENSG00000174720 | LARP7 | TCR signaling Pathwa... | 2.183e-03 | 3.712e-02 | 0.4341 | 0.9956 | protective | details |
| BLCA | ENSG00000107077 | KDM4C | TCR signaling Pathwa... | 1.869e-03 | 3.178e-02 | 0.4969 | 0.9963 | protective | details |
| BLCA | ENSG00000005302 | MSL3 | Chemokines | 1.689e-03 | 1.436e-02 | -0.4778 | -0.9966 | protective | details |
| BLCA | ENSG00000005302 | MSL3 | Cytokines | 1.488e-03 | 1.436e-02 | -0.4287 | -0.997 | protective | details |
| BLCA | ENSG00000157227 | MMP14 | Cytokines | 2.488e-03 | 2.208e-02 | 0.3757 | 0.995 | risk | details |
| BLCA | ENSG00000185787 | MORF4L1 | Antigen Processing a... | 1.821e-03 | 3.097e-02 | 0.4984 | 0.9964 | risk | details |
| BLCA | ENSG00000129559 | NEDD8 | Antigen Processing a... | 2.155e-03 | 3.664e-02 | 0.5021 | 0.9957 | risk | details |
| BLCA | ENSG00000158747 | NBL1 | Antimicrobials | 1.443e-03 | 9.413e-03 | 0.296 | 0.9971 | risk | details |
| BLCA | ENSG00000158747 | NBL1 | Chemokines | 1.661e-03 | 9.413e-03 | 0.4065 | 0.9967 | risk | details |
| BLCA | ENSG00000158747 | NBL1 | Cytokines | 1.451e-03 | 9.413e-03 | 0.3461 | 0.9971 | risk | details |
| BLCA | ENSG00000158747 | NBL1 | TCR signaling Pathwa... | 2.469e-03 | 1.049e-02 | -0.5001 | -0.9951 | risk | details |
| BLCA | ENSG00000167604 | NFKBID | Antigen Processing a... | 2.132e-03 | 3.625e-02 | -0.3641 | -0.9957 | protective | details |
| BLCA | ENSG00000166579 | NDEL1 | Interleukins | 2.475e-03 | 1.805e-02 | 0.5734 | 0.995 | risk | details |
| BLCA | ENSG00000136147 | PHF11 | Antigen Processing a... | 2.212e-03 | 1.893e-02 | 0.3971 | 0.9956 | protective | details |
| BLCA | ENSG00000136147 | PHF11 | Natural Killer Cell ... | 2.227e-03 | 1.893e-02 | 0.3601 | 0.9955 | protective | details |
| BLCA | ENSG00000136040 | PLXNC1 | Cytokine Receptors | 1.328e-03 | 1.218e-02 | 0.3498 | 0.9973 | risk | details |
| BLCA | ENSG00000136040 | PLXNC1 | TCR signaling Pathwa... | 1.433e-03 | 1.218e-02 | 0.4623 | 0.9971 | risk | details |
| BLCA | ENSG00000185619 | PCGF3 | Antigen Processing a... | 2.123e-03 | 3.609e-02 | -0.5287 | -0.9958 | protective | details |
| BLCA | ENSG00000123349 | PFDN5 | TCR signaling Pathwa... | 1.821e-03 | 3.097e-02 | -0.4021 | -0.9964 | protective | details |