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TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| BLCA | ENSG00000132485 | ZRANB2 | Antigen Processing a... | 2.326e-03 | 2.918e-02 | -0.4882 | -0.9953 | protective | details |
| BLCA | ENSG00000070366 | SMG6 | TCR signaling Pathwa... | 2.066e-03 | 3.512e-02 | 0.4172 | 0.9959 | risk | details |
| BLCA | ENSG00000185222 | TCEAL9 | Antimicrobials | 1.471e-03 | 1.012e-02 | 0.4089 | 0.9971 | protective | details |
| BLCA | ENSG00000185222 | TCEAL9 | Cytokines | 1.458e-03 | 1.012e-02 | 0.3768 | 0.9971 | protective | details |
| BLCA | ENSG00000185222 | TCEAL9 | Interleukins | 1.786e-03 | 1.012e-02 | 0.6466 | 0.9964 | protective | details |
| BRCA | ENSG00000123405 | NFE2 | Antimicrobials | 1.110e-03 | 9.434e-03 | 0.3564 | 0.9978 | protective | details |
| BRCA | ENSG00000123405 | NFE2 | Cytokines | 1.095e-03 | 9.434e-03 | 0.4114 | 0.9978 | protective | details |
| BRCA | ENSG00000164379 | FOXQ1 | Antimicrobials | 1.106e-03 | 6.722e-03 | 0.3889 | 0.9978 | protective | details |
| BRCA | ENSG00000164379 | FOXQ1 | Cytokines | 1.117e-03 | 6.722e-03 | 0.3911 | 0.9978 | protective | details |
| BRCA | ENSG00000164379 | FOXQ1 | Cytokine Receptors | 1.186e-03 | 6.722e-03 | 0.3312 | 0.9976 | protective | details |
| BRCA | ENSG00000267680 | ZNF224 | Antigen Processing a... | 2.132e-03 | 9.748e-03 | -0.3966 | -0.9957 | protective | details |
| BRCA | ENSG00000267680 | ZNF224 | Antimicrobials | 2.294e-03 | 9.748e-03 | -0.2844 | -0.9954 | protective | details |
| BRCA | ENSG00000267680 | ZNF224 | Natural Killer Cell ... | 2.053e-03 | 9.748e-03 | -0.3562 | -0.9959 | protective | details |
| BRCA | ENSG00000267680 | ZNF224 | TGFb Family Member R... | 1.931e-03 | 9.748e-03 | 0.6453 | 0.9961 | protective | details |
| BRCA | ENSG00000251192 | ZNF674 | Antigen Processing a... | 2.083e-03 | 1.211e-02 | -0.3528 | -0.9958 | risk | details |
| BRCA | ENSG00000251192 | ZNF674 | Antimicrobials | 2.092e-03 | 1.211e-02 | -0.2269 | -0.9958 | risk | details |
| BRCA | ENSG00000251192 | ZNF674 | Cytokines | 2.137e-03 | 1.211e-02 | -0.2393 | -0.9957 | risk | details |
| BRCA | ENSG00000173275 | ZNF449 | Antigen Processing a... | 2.083e-03 | 1.213e-02 | -0.4504 | -0.9958 | risk | details |
| BRCA | ENSG00000173275 | ZNF449 | Antimicrobials | 2.141e-03 | 1.213e-02 | -0.28 | -0.9957 | risk | details |
| BRCA | ENSG00000173275 | ZNF449 | Chemokines | 2.088e-03 | 1.213e-02 | -0.3413 | -0.9958 | risk | details |