Advanced searching
TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| BRCA | ENSG00000089775 | ZBTB25 | Antigen Processing a... | 1.887e-03 | 6.693e-03 | -0.3783 | -0.9962 | protective | details |
| BRCA | ENSG00000089775 | ZBTB25 | Antimicrobials | 1.916e-03 | 6.693e-03 | -0.3015 | -0.9962 | protective | details |
| BRCA | ENSG00000089775 | ZBTB25 | Chemokines | 1.969e-03 | 6.693e-03 | -0.3588 | -0.9961 | protective | details |
| BRCA | ENSG00000089775 | ZBTB25 | Cytokines | 1.855e-03 | 6.693e-03 | -0.2592 | -0.9963 | protective | details |
| BRCA | ENSG00000089775 | ZBTB25 | Interleukins Recepto... | 1.916e-03 | 6.693e-03 | -0.4134 | -0.9962 | protective | details |
| BRCA | ENSG00000186376 | ZNF75D | Antigen Processing a... | 2.232e-03 | 2.152e-02 | -0.3426 | -0.9955 | risk | details |
| BRCA | ENSG00000134317 | GRHL1 | Antimicrobials | 1.773e-03 | 5.286e-03 | 0.2756 | 0.9965 | risk | details |
| BRCA | ENSG00000134317 | GRHL1 | Chemokines | 1.835e-03 | 5.286e-03 | 0.3721 | 0.9963 | risk | details |
| BRCA | ENSG00000134317 | GRHL1 | Cytokine Receptors | 1.808e-03 | 5.286e-03 | 0.3043 | 0.9964 | risk | details |
| BRCA | ENSG00000134317 | GRHL1 | Interleukins Recepto... | 1.852e-03 | 5.286e-03 | 0.5086 | 0.9963 | risk | details |
| BRCA | ENSG00000134317 | GRHL1 | Natural Killer Cell ... | 1.821e-03 | 5.286e-03 | 0.3336 | 0.9964 | risk | details |
| BRCA | ENSG00000134317 | GRHL1 | TCR signaling Pathwa... | 1.866e-03 | 5.286e-03 | 0.4206 | 0.9963 | risk | details |
| BRCA | ENSG00000221869 | CEBPD | Antimicrobials | 1.515e-03 | 1.316e-02 | 0.2739 | 0.997 | protective | details |
| BRCA | ENSG00000221869 | CEBPD | Cytokines | 1.548e-03 | 1.316e-02 | 0.3391 | 0.9969 | protective | details |
| BRCA | ENSG00000256229 | ZNF486 | Antigen Processing a... | 2.132e-03 | 9.341e-03 | -0.3504 | -0.9957 | risk | details |
| BRCA | ENSG00000256229 | ZNF486 | Antimicrobials | 2.198e-03 | 9.341e-03 | -0.3235 | -0.9956 | risk | details |
| BRCA | ENSG00000256229 | ZNF486 | Chemokines | 2.096e-03 | 9.341e-03 | -0.3336 | -0.9958 | risk | details |
| BRCA | ENSG00000256229 | ZNF486 | Natural Killer Cell ... | 2.083e-03 | 9.341e-03 | -0.3324 | -0.9958 | risk | details |
| BRCA | ENSG00000179388 | EGR3 | Cytokines | 1.253e-03 | 1.135e-02 | 0.2952 | 0.9975 | protective | details |
| BRCA | ENSG00000179388 | EGR3 | Cytokine Receptors | 1.335e-03 | 1.135e-02 | 0.2968 | 0.9973 | protective | details |