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TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| BRCA | ENSG00000163508 | EOMES | Antigen Processing a... | 1.395e-03 | 3.300e-03 | 0.5668 | 0.9972 | protective | details |
| BRCA | ENSG00000163508 | EOMES | Antimicrobials | 1.156e-03 | 3.300e-03 | 0.4063 | 0.9977 | protective | details |
| BRCA | ENSG00000163508 | EOMES | BCR Signaling Pathwa... | 1.529e-03 | 3.300e-03 | 0.5701 | 0.9969 | protective | details |
| BRCA | ENSG00000163508 | EOMES | Chemokines | 1.453e-03 | 3.300e-03 | 0.4881 | 0.9971 | protective | details |
| BRCA | ENSG00000163508 | EOMES | Cytokine Receptors | 1.259e-03 | 3.300e-03 | 0.3926 | 0.9975 | protective | details |
| BRCA | ENSG00000163508 | EOMES | Interleukins Recepto... | 1.553e-03 | 3.300e-03 | 0.6797 | 0.9969 | protective | details |
| BRCA | ENSG00000163508 | EOMES | Natural Killer Cell ... | 1.404e-03 | 3.300e-03 | 0.5732 | 0.9972 | protective | details |
| BRCA | ENSG00000163508 | EOMES | TCR signaling Pathwa... | 1.477e-03 | 3.300e-03 | 0.6429 | 0.997 | protective | details |
| BRCA | ENSG00000166925 | TSC22D4 | Chemokines | 2.101e-03 | 1.670e-02 | 0.3271 | 0.9958 | protective | details |
| BRCA | ENSG00000269404 | SPIB | Antigen Processing a... | 1.675e-03 | 4.868e-03 | 0.4029 | 0.9966 | protective | details |
| BRCA | ENSG00000269404 | SPIB | Antimicrobials | 1.572e-03 | 4.868e-03 | 0.3408 | 0.9969 | protective | details |
| BRCA | ENSG00000269404 | SPIB | Chemokines | 1.704e-03 | 4.868e-03 | 0.4365 | 0.9966 | protective | details |
| BRCA | ENSG00000269404 | SPIB | Interleukins Recepto... | 1.718e-03 | 4.868e-03 | 0.4774 | 0.9966 | protective | details |
| BRCA | ENSG00000269404 | SPIB | Natural Killer Cell ... | 1.667e-03 | 4.868e-03 | 0.4453 | 0.9967 | protective | details |
| BRCA | ENSG00000269404 | SPIB | TCR signaling Pathwa... | 1.704e-03 | 4.868e-03 | 0.4652 | 0.9966 | protective | details |
| BRCA | ENSG00000269404 | SPIB | TGFb Family Member R... | 2.212e-03 | 5.373e-03 | -0.6385 | -0.9956 | protective | details |
| BRCA | ENSG00000127152 | BCL11B | Antimicrobials | 1.431e-03 | 5.705e-03 | 0.3418 | 0.9971 | protective | details |
| BRCA | ENSG00000127152 | BCL11B | Chemokines | 1.672e-03 | 5.705e-03 | 0.391 | 0.9967 | protective | details |
| BRCA | ENSG00000127152 | BCL11B | Interleukins Recepto... | 1.678e-03 | 5.705e-03 | 0.5895 | 0.9966 | protective | details |
| BRCA | ENSG00000127152 | BCL11B | Natural Killer Cell ... | 1.631e-03 | 5.705e-03 | 0.397 | 0.9967 | protective | details |