Advanced searching
TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| BRCA | ENSG00000168310 | IRF2 | TCR signaling Pathwa... | 2.433e-03 | 4.136e-02 | 0.3783 | 0.9951 | protective | details |
| BRCA | ENSG00000188070 | C11orf95 | Antigen Processing a... | 2.398e-03 | 1.359e-02 | -0.5285 | -0.9952 | risk | details |
| BRCA | ENSG00000188070 | C11orf95 | Cytokines | 1.536e-03 | 1.359e-02 | 0.3377 | 0.9969 | risk | details |
| BRCA | ENSG00000188070 | C11orf95 | Cytokine Receptors | 1.608e-03 | 1.359e-02 | 0.3212 | 0.9968 | risk | details |
| BRCA | ENSG00000180855 | ZNF443 | Antigen Processing a... | 2.105e-03 | 1.193e-02 | -0.3967 | -0.9958 | risk | details |
| BRCA | ENSG00000180855 | ZNF443 | Antimicrobials | 2.045e-03 | 1.193e-02 | -0.2921 | -0.9959 | risk | details |
| BRCA | ENSG00000180855 | ZNF443 | Cytokines | 2.058e-03 | 1.193e-02 | -0.2503 | -0.9959 | risk | details |
| BRCA | ENSG00000236609 | ZNF853 | Cytokines | 1.181e-03 | 1.250e-02 | 0.3097 | 0.9976 | protective | details |
| BRCA | ENSG00000236609 | ZNF853 | TGFb Family Member | 1.563e-03 | 1.250e-02 | 0.5755 | 0.9969 | protective | details |
| BRCA | ENSG00000197054 | ZNF763 | Antigen Processing a... | 2.439e-03 | 1.214e-02 | -0.4078 | -0.9951 | protective | details |
| BRCA | ENSG00000197054 | ZNF763 | Natural Killer Cell ... | 2.481e-03 | 1.214e-02 | -0.4129 | -0.995 | protective | details |
| BRCA | ENSG00000197054 | ZNF763 | TCR signaling Pathwa... | 2.410e-03 | 1.214e-02 | -0.3442 | -0.9952 | protective | details |
| BRCA | ENSG00000186300 | ZNF555 | Antigen Processing a... | 2.137e-03 | 1.276e-02 | -0.4379 | -0.9957 | risk | details |
| BRCA | ENSG00000186300 | ZNF555 | Antimicrobials | 2.252e-03 | 1.276e-02 | -0.2897 | -0.9955 | risk | details |
| BRCA | ENSG00000186300 | ZNF555 | Chemokines | 2.096e-03 | 1.276e-02 | -0.3096 | -0.9958 | risk | details |
| BRCA | ENSG00000198846 | TOX | Antimicrobials | 1.431e-03 | 6.018e-03 | 0.2639 | 0.9971 | protective | details |
| BRCA | ENSG00000198846 | TOX | Chemokines | 1.656e-03 | 6.018e-03 | 0.3873 | 0.9967 | protective | details |
| BRCA | ENSG00000198846 | TOX | Interleukins Recepto... | 1.770e-03 | 6.018e-03 | 0.539 | 0.9965 | protective | details |
| BRCA | ENSG00000198846 | TOX | Natural Killer Cell ... | 1.621e-03 | 6.018e-03 | 0.3742 | 0.9968 | protective | details |
| BRCA | ENSG00000198846 | TOX | TCR signaling Pathwa... | 1.698e-03 | 6.018e-03 | 0.5065 | 0.9966 | protective | details |