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TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| BRCA | ENSG00000083307 | GRHL2 | TCR signaling Pathwa... | 1.965e-03 | 3.340e-02 | 0.5149 | 0.9961 | risk | details |
| BRCA | ENSG00000147601 | TERF1 | Cytokines | 1.553e-03 | 2.640e-02 | -0.2754 | -0.9969 | risk | details |
| BRCA | ENSG00000156127 | BATF | Antigen Processing a... | 1.988e-03 | 3.380e-02 | 0.2833 | 0.996 | protective | details |
| BRCA | ENSG00000125347 | IRF1 | Antigen Processing a... | 2.045e-03 | 4.502e-03 | 0.5734 | 0.9959 | protective | details |
| BRCA | ENSG00000125347 | IRF1 | Antimicrobials | 2.119e-03 | 4.502e-03 | 0.3441 | 0.9958 | protective | details |
| BRCA | ENSG00000125347 | IRF1 | Interleukins | 2.024e-03 | 4.502e-03 | 0.5376 | 0.996 | protective | details |
| BRCA | ENSG00000125347 | IRF1 | Interleukins Recepto... | 2.037e-03 | 4.502e-03 | 0.4494 | 0.9959 | protective | details |
| BRCA | ENSG00000125347 | IRF1 | Natural Killer Cell ... | 2.083e-03 | 4.502e-03 | 0.465 | 0.9958 | protective | details |
| BRCA | ENSG00000125347 | IRF1 | TCR signaling Pathwa... | 2.070e-03 | 4.502e-03 | 0.4064 | 0.9959 | protective | details |
| BRCA | ENSG00000125347 | IRF1 | TGFb Family Member | 2.041e-03 | 4.502e-03 | -0.619 | -0.9959 | protective | details |
| BRCA | ENSG00000125347 | IRF1 | TNF Family Members R... | 2.037e-03 | 4.502e-03 | 0.6228 | 0.9959 | protective | details |
| BRCA | ENSG00000028277 | POU2F2 | Antimicrobials | 1.553e-03 | 9.787e-03 | 0.311 | 0.9969 | protective | details |
| BRCA | ENSG00000028277 | POU2F2 | Natural Killer Cell ... | 1.727e-03 | 9.787e-03 | 0.4015 | 0.9965 | protective | details |
| BRCA | ENSG00000028277 | POU2F2 | TCR signaling Pathwa... | 1.727e-03 | 9.787e-03 | 0.4701 | 0.9965 | protective | details |
| BRCA | ENSG00000142528 | ZNF473 | TCR signaling Pathwa... | 2.309e-03 | 3.926e-02 | 0.4743 | 0.9954 | risk | details |
| BRCA | ENSG00000182979 | MTA1 | Cytokines | 1.645e-03 | 1.577e-02 | 0.2508 | 0.9967 | protective | details |
| BRCA | ENSG00000182979 | MTA1 | TNF Family Members R... | 1.855e-03 | 1.577e-02 | 0.6057 | 0.9963 | protective | details |
| BRCA | ENSG00000198300 | PEG3 | TGFb Family Member R... | 1.739e-03 | 1.697e-02 | 0.6673 | 0.9965 | risk | details |
| BRCA | ENSG00000077092 | RARB | Cytokine Receptors | 1.842e-03 | 1.109e-02 | 0.3902 | 0.9963 | protective | details |
| BRCA | ENSG00000077092 | RARB | Interleukins Recepto... | 1.957e-03 | 1.109e-02 | 0.5497 | 0.9961 | protective | details |