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TF List
The enrichment of TFs in the immune pathways across cancer types
Description:
'ES value' refers to the enrichment score.
'Score' refers to the integrated enrichment score (when ES>0, Score=1-2*p; when ES<0, Score=2*p-1).
'Survival' refers to the K-M survival curve of regulons in the corresponding cancer.
'Detail' refers to the enrichment plot and marker genes.
| Cancer | TF ID | Symbol | Immune Pathway | P value | FDR value | ES value | Score | Survival | Detail |
|---|---|---|---|---|---|---|---|---|---|
| ACC | ENSG00000173757 | STAT5B | Cytokine Receptors | 2.353e-03 | 1.882e-02 | 0.361 | 0.9953 | protective | details |
| ACC | ENSG00000112837 | TBX18 | Interleukins Recepto... | 2.463e-03 | 9.195e-03 | -0.5661 | -0.9951 | risk | details |
| ACC | ENSG00000131910 | NR0B2 | Antigen Processing a... | 1.449e-03 | 1.365e-02 | 0.5553 | 0.9971 | protective | details |
| ACC | ENSG00000131910 | NR0B2 | TGFb Family Member R... | 1.706e-03 | 1.365e-02 | 0.811 | 0.9966 | protective | details |
| ACC | ENSG00000012223 | LTF | Cytokine Receptors | 1.261e-03 | 2.018e-02 | 0.4553 | 0.9975 | protective | details |
| ACC | ENSG00000102901 | CENPT | Antigen Processing a... | 1.996e-03 | 3.194e-02 | -0.4697 | -0.996 | risk | details |
| ACC | ENSG00000115816 | CEBPZ | Natural Killer Cell ... | 1.541e-03 | 2.465e-02 | -0.4134 | -0.9969 | risk | details |
| ACC | ENSG00000116016 | EPAS1 | Cytokine Receptors | 1.259e-03 | 2.015e-02 | 0.4188 | 0.9975 | protective | details |
| ACC | ENSG00000124201 | ZNFX1 | Antigen Processing a... | 1.515e-03 | 2.424e-02 | 0.5339 | 0.997 | protective | details |
| ACC | ENSG00000125826 | RBCK1 | Antigen Processing a... | 1.377e-03 | 1.102e-02 | 0.4751 | 0.9972 | protective | details |
| ACC | ENSG00000125826 | RBCK1 | Antimicrobials | 2.312e-03 | 1.233e-02 | 0.3573 | 0.9954 | protective | details |
| ACC | ENSG00000125826 | RBCK1 | Natural Killer Cell ... | 1.377e-03 | 1.102e-02 | 0.4952 | 0.9972 | protective | details |
| ACC | ENSG00000146285 | SCML4 | Natural Killer Cell ... | 1.200e-03 | 9.963e-03 | 0.5133 | 0.9976 | protective | details |
| ACC | ENSG00000146285 | SCML4 | TCR signaling Pathwa... | 1.245e-03 | 9.963e-03 | 0.5312 | 0.9975 | protective | details |
| ACC | ENSG00000134874 | DZIP1 | Antigen Processing a... | 1.866e-03 | 2.985e-02 | -0.4777 | -0.9963 | risk | details |
| ACC | ENSG00000151657 | KIN | Antimicrobials | 1.294e-03 | 2.070e-02 | -0.3738 | -0.9974 | risk | details |
| ACC | ENSG00000151789 | ZNF385D | Natural Killer Cell ... | 1.145e-03 | 9.569e-03 | 0.5452 | 0.9977 | protective | details |
| ACC | ENSG00000151789 | ZNF385D | TCR signaling Pathwa... | 1.196e-03 | 9.569e-03 | 0.5166 | 0.9976 | protective | details |
| ACC | ENSG00000118058 | KMT2A | Antigen Processing a... | 1.597e-03 | 2.556e-02 | -0.51 | -0.9968 | risk | details |
| ACC | ENSG00000171169 | NAIF1 | Antigen Processing a... | 1.855e-03 | 2.968e-02 | 0.5563 | 0.9963 | protective | details |