The rapid advent spatially resolved transcriptomics techniques have given rise to map transcripts at single-cell resolution in various types of cancer. By curating 203 datasets from 20 cancer types, we assembled a comprehensive spatial meta-transcriptome resource integrating 334,253 spots, 1,908,646 cells, and the distribution and abundance of 1,218 microbiota in spatial tissue slices. We construct SMTdb, to enable vast interactively data exploration of spatial distribution and expression of microbiota, host gene modules associated with certain microbiota and co-occurrence between microbiota and immune cells within tumor microenvironment. The atlas resource serves as a one-stop and time-effective platform to investigate the interactions among microbial ecosystems and host.
