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Description for ‘mode of action’：the ‘mode of action’ for signature is composed of three parts: A_B_C.
A describes the level at which the corresponding signature changes, it may contain the following values: TRAN(translation),
PROT(protein), CE(cell), METH(methylation), AC(acetylation), PHOS(phosphorylation), MU(mutation), SNP(single nucleotide polymorphism),
GLYC(glycosylation) and PATH(pathway). B describes the corresponding signature in which cancer immunotherapy condition group has changed,
it may contain the following values: R (immunotherapy response group), NR(immunotherapy non-response group), D (Immunotherapy group),
ND (No immunotherapy group). C describes the change detail (specific direction) of the corresponding signature, it may contain the
following values: UP (High gene/protein expression or increased cellular abundance or enhanced epigenetic modification),
DN (Low gene/protein expression or reduced cellular abundance or attenuated epigenetic modifications), LOSS (deletion mutation),
GAIN (gain mutation)，Other. For example, the search/browse detail result for CD274 was “PROT_R_UP”, it can be interpreted that
the protein level of CD274 was upregulated in immunotherapy response individuals.
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