Welcome to CiTSA 1.0!
CiTSA, a comprehensive resource, which can provide a wealth of information about experimentally
supported cancer immunotherapy signatures and also provide analysis tools based on single cell
and bulk datasets. CiTSA stores 878 entries of experimentally supported associations between 412
signatures and 177 treatments of five mian immunotherapy categories across 30 cancer types.
CiTSA also provides flexible online tools to identify and visualize molecular/cell feature and
interaction, to perform function, correlation and survival analysis, and to execute cell clustering,
cluster activity and cell-cell communication analysis based on single cell (307485 cells from 7
cancer types) and bulk (1045 samples from 16 cancer types) datasets. CiTSA provides a comprehensive
and high-quality resource for studying biology molecules/cells act in tumor immunity and immunotherapy,
and is helpful for understanding the molecular mechanism, discovering biomarkers, developing novel
therapeutic targets and achieving the precision immunotherapy.
Analysis Tools
Experimentally supported signatures of cancer immunotherapy
878 entries
412 signatures
30 cancer types
5 immunotherapy types
Cancer immunotherapy and treatment
Immunotherapy types
immune checkpoint therapy (12 treatments/drugs)
adoptive cell therapy (36 treatments/drugs)
cancer vaccine (30 treatments/drugs)
oncolytic viruses (22 treatments/drugs)
immunostimulant or targeting (63 treatments/drugs)
combined immunotherapy (20 treatments/drugs)
Immunotherapy conditions
response/non-response
treatment/non-treatment
Cancer immunotherapy datasets
13 single cell datasets
164 samples
307485 cells
7 cancer types
35 bulk datasets
1045 samples
16 cancer types