stSNV provides a versatile resource of somatic SNVs (single nucleotide variants) at spatial transcriptomics resolution, involving 42,202 genes in 730,067 spots, covering 36 diseases and 39 normal tissues. Based on a large spatial multicellular dataset, stSNV performs multilevel analyses to provide insights into the spatial variation function in different types of human and mouse tissues, and user-friendly comprehensive analysis tools were equipped in the database.
stSNV constructed a comprehensive Spot-SNVs Count Matrix for human tissues, revealing mutational clusters and their unique characteristics, exploring the profound impact of SNVs on gene expression, showcasing the co-localization between SNVs and cells, and screening for key SNVs in spatial communication.
