Data type Species Disease Gene Title Result PMID Details
mRNA Homo sapiens MS HLA-DPB1 HLA-DP-associated susceptibility to the opticespinal form of multiple sclerosis in the Japanese Our data provide further evidence that Asian and Western type MS are distinct regarding the immunogenetic background. 9756407 Details
mRNA Homo sapiens MS HLA-DPB1 HLA-DPB1*0501-associated opticospinal multiple sclerosis: clinical, neuroimaging and immunogenetic studies The marked differences in the clinical and MRI findings as well as in the immunogenetic backgrounds between the opticospinal multiple sclerosis and Western-type multiple sclerosis together suggest that HLA-DPB1*0501-associated opticospinal multiple sclerosis is a distinct subtype of multiple sclerosis. 10468508 Details
mRNA Homo sapiens MS HLA-DPB1 FREQUENCY OF HLA-DPB1 ALLELES IN MULTIPLE SCLEROSIS PATIENTS FROM NORTHERN IRELAND Although present in the controls, linkage disequilibrium between HLA-DPBl*OlOl and HLA-DR17 was not found in multiple sclerosis patients. 1420118 Details
Variants Homo sapiens MS HLA-DPB1 HLAs and genes in Japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1*0602 The frequencies of all of the residues in each variable region of the amino acid sequences of DQβ and DPβ chains were not different between the MS patients and the controls. 1286977 Details
Variants Homo sapiens MS HLA-DPB1 HLAs and genes in Japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1*0602 The frequencies of all of the residues in each variable region of the amino acid sequences of DQβ and DPβ chains were not different between the MS patients and the controls. 1286977 Details
Variants Homo sapiens MS HLA-DPB1 HLAs and genes in Japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1*0602 The frequencies of all of the residues in each variable region of the amino acid sequences of DQβ and DPβ chains were not different between the MS patients and the controls. 1286977 Details
Variants Homo sapiens MS HLA-DPB1 HLAs and genes in Japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1*0602 The frequencies of all of the residues in each variable region of the amino acid sequences of DQβ and DPβ chains were not different between the MS patients and the controls. 1286977 Details
Variants Homo sapiens MS HLA-DPB1 HLAs and genes in Japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1*0602 The frequencies of all of the residues in each variable region of the amino acid sequences of DQβ and DPβ chains were not different between the MS patients and the controls. 1286977 Details
Variants Homo sapiens MS HLA-DPB1 HLAs and genes in Japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1*0602 The frequencies of all of the residues in each variable region of the amino acid sequences of DQβ and DPβ chains were not different between the MS patients and the controls. 1286977 Details
Variants Homo sapiens MS HLA-DPB1 HLAs and genes in Japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1*0602 The frequencies of all of the residues in each variable region of the amino acid sequences of DQβ and DPβ chains were not different between the MS patients and the controls. 1286977 Details
Variants Homo sapiens MS HLA-DPB1 HLAs and genes in Japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1*0602 The frequencies of all of the residues in each variable region of the amino acid sequences of DQβ and DPβ chains were not different between the MS patients and the controls. 1286977 Details
Variants Homo sapiens MS HLA-DPB1 HLAs and genes in Japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1*0602 The frequencies of all of the residues in each variable region of the amino acid sequences of DQβ and DPβ chains were not different between the MS patients and the controls. 1286977 Details
Variants Homo sapiens MS HLA-DPB1 HLAs and genes in Japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1*0602 The frequencies of all of the residues in each variable region of the amino acid sequences of DQβ and DPβ chains were not different between the MS patients and the controls. 1286977 Details
Variants Homo sapiens MS HLA-DPB1 HLAs and genes in Japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1*0602 The frequencies of all of the residues in each variable region of the amino acid sequences of DQβ and DPβ chains were not different between the MS patients and the controls. 1286977 Details
Variants Homo sapiens MS HLA-DPB1 HLAs and genes in Japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1*0602 The frequencies of all of the residues in each variable region of the amino acid sequences of DQβ and DPβ chains were not different between the MS patients and the controls. 1286977 Details
Variants Homo sapiens MS HLA-DPB1 HLAs and genes in Japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1*0602 The frequencies of all of the residues in each variable region of the amino acid sequences of DQβ and DPβ chains were not different between the MS patients and the controls. 1286977 Details
Variants Homo sapiens MS HLA-DPB1 HLAs and genes in Japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1*0602 The frequencies of all of the residues in each variable region of the amino acid sequences of DQβ and DPβ chains were not different between the MS patients and the controls. 1286977 Details
Variants Homo sapiens MS HLA-DPB1 HLAs and genes in Japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1*0602 The frequencies of all of the residues in each variable region of the amino acid sequences of DQβ and DPβ chains were not different between the MS patients and the controls. 1286977 Details
Variants Homo sapiens MS HLA-DPB1 HLAs and genes in Japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1*0602 The frequencies of all of the residues in each variable region of the amino acid sequences of DQβ and DPβ chains were not different between the MS patients and the controls. 1286977 Details
Variants Homo sapiens MS HLA-DPB1 HLAs and genes in Japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1*0602 The frequencies of all of the residues in each variable region of the amino acid sequences of DQβ and DPβ chains were not different between the MS patients and the controls. 1286977 Details
Variants Homo sapiens MS HLA-DPB1 HLAs and genes in Japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1*0602 The frequencies of all of the residues in each variable region of the amino acid sequences of DQβ and DPβ chains were not different between the MS patients and the controls. 1286977 Details
Variants Homo sapiens MS HLA-DPB1 HLAs and genes in Japanese patients with multiple sclerosis: evidence for increased frequencies of HLA-Cw3, HLA-DR2, and HLA-DQB1*0602 The frequencies of all of the residues in each variable region of the amino acid sequences of DQβ and DPβ chains were not different between the MS patients and the controls. 1286977 Details
Variants Homo sapiens MS HLA-DPB1 Vitamin D receptor gene polymorphism in multiple sclerosis and the association with HLA class II alleles HLA alleles may correlate with risk for MS together with VDRG. 10967184 Details
Variants Homo sapiens MS HLA-DPB1 Vitamin D receptor gene polymorphism in multiple sclerosis and the association with HLA class II alleles HLA alleles may correlate with risk for MS together with VDRG. 10967184 Details
Variants Homo sapiens MS HLA-DPB1 Vitamin D receptor gene polymorphism in multiple sclerosis and the association with HLA class II alleles HLA alleles may correlate with risk for MS together with VDRG. 10967184 Details
Variants Homo sapiens MS HLA-DPB1 Vitamin D receptor gene polymorphism in multiple sclerosis and the association with HLA class II alleles HLA alleles may correlate with risk for MS together with VDRG. 10967184 Details
Variants Homo sapiens MS HLA-DPB1 Vitamin D receptor gene polymorphism in multiple sclerosis and the association with HLA class II alleles HLA alleles may correlate with risk for MS together with VDRG. 10967184 Details
Variants Homo sapiens MS HLA-DPB1 Vitamin D receptor gene polymorphism in multiple sclerosis and the association with HLA class II alleles HLA alleles may correlate with risk for MS together with VDRG. 10967184 Details
Variants Homo sapiens MS HLA-DPB1 Vitamin D receptor gene polymorphism in multiple sclerosis and the association with HLA class II alleles HLA alleles may correlate with risk for MS together with VDRG. 10967184 Details
Variants Homo sapiens MS HLA-DPB1 Vitamin D receptor gene polymorphism in multiple sclerosis and the association with HLA class II alleles HLA alleles may correlate with risk for MS together with VDRG. 10967184 Details
Variants Homo sapiens MS HLA-DPB1 Vitamin D receptor gene polymorphism in multiple sclerosis and the association with HLA class II alleles HLA alleles may correlate with risk for MS together with VDRG. 10967184 Details
Variants Homo sapiens MS HLA-DPB1 Vitamin D receptor gene polymorphism in multiple sclerosis and the association with HLA class II alleles HLA alleles may correlate with risk for MS together with VDRG. 10967184 Details
Variants Homo sapiens MS HLA-DPB1 Vitamin D receptor gene polymorphism in multiple sclerosis and the association with HLA class II alleles HLA alleles may correlate with risk for MS together with VDRG. 10967184 Details
Variants Homo sapiens MS HLA-DPB1 Vitamin D receptor gene polymorphism in multiple sclerosis and the association with HLA class II alleles HLA alleles may correlate with risk for MS together with VDRG. 10967184 Details
Variants Homo sapiens MS HLA-DPB1 Vitamin D receptor gene polymorphism in multiple sclerosis and the association with HLA class II alleles HLA alleles may correlate with risk for MS together with VDRG. 10967184 Details
Variants Homo sapiens MS HLA-DPB1 A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis we identified seven SNPs that were independently associated with MS conditional on the others. 21049023 Details
Variants Homo sapiens MS HLA-DPB1 A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis we identified seven SNPs that were independently associated with MS conditional on the others. 21049023 Details
Variants Homo sapiens MS HLA-DPB1 A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis we identified seven SNPs that were independently associated with MS conditional on the others. 21049023 Details
Variants Homo sapiens MS HLA-DPB1 A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis we identified seven SNPs that were independently associated with MS conditional on the others. 21049023 Details
Variants Homo sapiens MS HLA-DPB1 A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis we identified seven SNPs that were independently associated with MS conditional on the others. 21049023 Details
Variants Homo sapiens MS HLA-DPB1 A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis we identified seven SNPs that were independently associated with MS conditional on the others. 21049023 Details
Variants Homo sapiens MS HLA-DPB1 A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis we identified seven SNPs that were independently associated with MS conditional on the others. 21049023 Details
Variants Homo sapiens MS HLA-DPB1 Class II HLA-DC beta-chain DNA restriction fragments differentiate among HLA-DR2 individuals in insulin-dependent diabetes and multiple sclerosis phenotype DR2(+), DC 2.2(-) is significantly more frequent in MS but not different in IDD. 6324215 Details
Variants Homo sapiens MS HLA-DPB1 Class II HLA-DC beta-chain DNA restriction fragments differentiate among HLA-DR2 individuals in insulin-dependent diabetes and multiple sclerosis phenotype DR2(+), DC 2.2(-) is significantly more frequent in MS but not different in IDD. 6324215 Details
Variants Homo sapiens MS HLA-DPB1 Interferon beta-1b exacerbates multiple sclerosis with severe optic nerve and spinal cord demyelination MS with DPB10501 showed severe optic neuritis, myelitis and CSF pleocytosis 17125797 Details
Variants Homo sapiens MS HLA-DPB1 Immunogenetics of multiple sclerosis and optic neuritis: DNA polymorphism of HLA class II genes The frequencies in MS of DPw4- associated DNA fragments were not significantly increased although the RR of DPAI*0103 was 2.9 (not significant) and DPB1*04 was 2.5 (not significant). 1349586 Details
Variants Homo sapiens MS HLA-DPB1 Association of the HLA-DRB1 alleles with characteristic MRI features of Asian multiple sclerosis None of the DPB1 alleles differed significantly among groups. 18952831 Details
Variants Homo sapiens MS HLA-DPB1 Both the HLA-DPB1 and -DRB1 alleles correlate with risk for multiple sclerosis in Japanese: clinical phenotypes and gender as important factors DRB1*1501 was not associated with DPB1*0301 nor DPB1*0501 in either patients or controls (data not shown), and the linkage disequilibria between these alleles were also not found in a large Japanese population 10777094 Details
Variants Homo sapiens MS HLA-DPB1 Both the HLA-DPB1 and -DRB1 alleles correlate with risk for multiple sclerosis in Japanese: clinical phenotypes and gender as important factors DRB1*1501 was not associated with DPB1*0301 nor DPB1*0501 in either patients or controls (data not shown), and the linkage disequilibria between these alleles were also not found in a large Japanese population 10777094 Details
Variants Homo sapiens MS HLA-DPB1 Both the HLA-DPB1 and -DRB1 alleles correlate with risk for multiple sclerosis in Japanese: clinical phenotypes and gender as important factors DRB1*1501 was not associated with DPB1*0301 nor DPB1*0501 in either patients or controls (data not shown), and the linkage disequilibria between these alleles were also not found in a large Japanese population 10777094 Details
Variants Homo sapiens MS HLA-DPB1 Expression of HLA-DP in patients with neuromyelitis optica spectrum disorders There was no statistically significant difference of the distributions of HLA-DPB1*0501/HLA-DPB1*0501, HLA-DPB1*0501/X and X/X genotypes and the frequencies of allele of HLA-DPB1*0501 among NMOSD, MS patients and healthy controls (P=0.96 and 0.71, respectively). 31826574 Details
Variants Homo sapiens MS HLA-DPB1 HLA-DRB1, -DQA1, -DQBl, =-DPA1 and -DPBl genes in Japanese multiple sclerosis patients Japanese MS patients and controls were examined for the distribution of HLA-DRBl, -DQAl, - DQBl, -DPAl and -DPB1 alleles using in vitro amplification of genomic DNA and probing with sequence-specific oligonucleotides. No significant difference in frequency of the examined alleles was observed among the two groups. 1926126 Details
Variants Homo sapiens MS HLA-DPB1 HLA-DPB1 gene polymorphism and multiple sclerosis: a large case-control study in the southwest of France The distribution of the DPB1 alleles was not significantly different in multiple sclerosis patients and controls (p = 0.11). 1918327 Details
Variants Homo sapiens MS HLA-DPB1 HLA-DR beta, -DQ alpha, and -DQ beta restriction fragment length polymorphisms in multiple sclerosis We detected no polymorphisms of DR beta, DQ alpha, or DQ beta genes among the DR2+ MS patients which distinguished them from normals. 2568496 Details
Variants Homo sapiens MS HLA-DPB1 HLA-DP beta and susceptibility to multiple sclerosis: an analysis of caucasoid and Japanese patient populations In contrast to previous reports, no DP beta allele was found to be increased in either patient population. 2391251 Details
Variants Homo sapiens MS HLA-DPB1 HLA-DPB1*0501-associated opticospinal multiple sclerosis: clinical, neuroimaging and immunogenetic studies The marked differences in the clinical and MRI findings as well as in the immunogenetic backgrounds between the opticospinal multiple sclerosis and Western-type multiple sclerosis together suggest that HLA-DPB1*0501-associated opticospinal multiple sclerosis is a distinct subtype of multiple sclerosis. 10468508 Details
Variants Homo sapiens MS HLA-DPB1 An Allelic Cluster of DQa Restriction Fragments Is Associated with Multiple Sclerosis: Evidence That a Second Haplotype May Influence Disease Susceptibility No polymorphism discriminating between MS and control pools was seen using DRB, DPa, DPB, TcRa, orTcRB geneprobes 2567726 Details
Variants Homo sapiens MS HLA-DPB1 FREQUENCY OF HLA-DPB1 ALLELES IN MULTIPLE SCLEROSIS PATIENTS FROM NORTHERN IRELAND Using sequence-specific oligonucleotide probes, no altered distribution in the frequency of HLA-DPB1 alleles was found in multiple sclerosis patients from Northern Ireland. Although present in the controls, linkage disequilibrium between HLA-DPBl*OlOl and HLA-DR17 was not found in multiple sclerosis patients. 1420118 Details