SDMap-Search tool enables users to search the association between drug perturbation and spatial spots/cells within a tissue slice by inputting the tissue, sample (slice), and drug name. Additionally, users can also input their interested drug target genes to find drugs of interest.MOA (Mechanism of Action) refers to how a drug or bioactive molecule produces its biological effects. It outlines the molecule’s target (e.g., a specific protein, enzyme, or receptor), the signaling/metabolic pathways it modulates, and resulting molecular changes (e.g., protein activation/inhibition, gene expression regulation).